Protein Alignment Cyp11b2 and Cyp49a1

DIOPT Version :9

• Sequence 1: NP_036670.2
• Gene: Cyp11b2 / 24294
• RGDID: 2454
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_001246256.1
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 132/495 - (26%)
• Similarity: 229/495 - (46%)
• Gaps: 65/495 - (13%)

  Rat    28 TTATLAP--KTLKPFEAIPQYSR-----------NKW--LKMIQILREQGQENLHLEMHQAFQEL 77
            |||:..|  .|..|..|:..||.           |.|  ..:|...:....:.:..|:|..:.::
  Fly    80 TTASSLPAETTSSPAAAVRPYSEVPGPYPLPLIGNSWRFAPLIGTYKISDLDKVMNELHVNYGKM 144

  Rat    78 GPIFRHSAGG----AQIVSVMLPEDAEKLHQVESILPRRMHLEPWVAH------RELRGLRRGVF 132
            ..:     ||    ..::.|...::...:.:.|..:|.|..: |.:.|      |:..|...|:.
  Fly   145 AKV-----GGLIGHPDLLFVFDGDEIRNIFKKEEAMPHRPSM-PSLRHYKGDLRRDFFGDVAGLI 203

  Rat   133 LLNGADWRFNRLKLNPNVLSPKAVQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQQSLFNY 197
            .::|..|...|.::...:|.|:..:.::|.::::|.:|:..:  ::.::.:..|..:....|:.:
  Fly   204 GVHGPKWEAFRQEVQHILLQPQTAKKYIPPLNDIASEFMGRI--ELMRDEKDELPANFLHELYKW 266

  Rat   198 TIEASNFALFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQL-LFLPRSLTRWTSTRVWKEHFDA 261
            .:|:........|||.|..:.:..:.:.|.|:::.|.:..:| |.:|  |.|...|:.::....|
  Fly   267 ALESVGRVSLDTRLGCLSPEGSEEAQQIIEAINTFFWAVPELELRMP--LWRIYPTKAYRSFVKA 329

  Rat   262 WDVISEYANRCIWKV-----HQELR-LGSSQTYSGIVAALITQ-GALPLDAIKANSMELTAGSVD 319
            .|..:....:.|.|.     ..|.| |..|:....||..::.: |...|.||.|  ::|....||
  Fly   330 LDQFTAICMKNIGKTMDKADADEARGLSKSEADISIVERIVRKTGNRKLAAILA--LDLFLVGVD 392

  Rat   320 TTAIPLVMTLFELARNPDVQQALRQETLAA----EASIAANPQKAMSDLPLLRAALKETLRLYPV 380
            ||::....|:::||:|||.|:.|..|....    ||.|   .|..:..:|.|||.:|||||:.||
  Fly   393 TTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADI---NQNVLEQMPYLRACVKETLRMRPV 454

  Rat   381 GGFLERILNSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLERK----------- 434
            .....|.|.||.|:..||||.||.|:.....:..:||.||.|:|::|:|||::.
  Fly   455 VIANGRSLQSDAVINGYHVPKGTHVIFPHLVVSNDPAYFPEPKRFLPERWLKQSTDAAGCPHANQ 519

  Rat   435 --RSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQV 472
              ..|..|.||||.|.|:|||.||:|:..||..:.:.::|
  Fly   520 KIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKV 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp11b2	NP_036670.2	p450	44..498	CDD:278495	125/477 (26%)
Cyp49a1	NP_001246256.1	p450	104..565	CDD:299894	123/471 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820