DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpb1 and CG4408

DIOPT Version :9

Sequence 1:	NP_036665.2	Gene:	Cpb1 / 24271	RGDID:	2391	Length:	415	Species:	Rattus norvegicus
Sequence 2:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	440	Identity:	132/440 - (30%)
Similarity:	226/440 - (51%)	Gaps:	44/440 - (10%)

- Green bases have known domain annotations that are detailed below.

  Rat     2 LLLLALVSVAL-------------------------AHASEEHFDGNRVYRVSVHGEDHVNLIQE 41
            ||||.:.||.:                         |.:.:..:|..|:|:|.:..|:||.|.|.
  Fly    38 LLLLLVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELASEEHVRLFQA 102

  Rat    42 LANTKEIDFWKPDSATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQF--- 103
            |....:...:...:....:.||.:   |....|||.::.:....|.:.||..|.:..:::.:
  Fly   103 LEQASDSCSFMGHARQPGQKLTIM---VTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEV 164

  Rat   104 -DSHTRASGHSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGKTRPNKPAI 167
             ...|:.....:.:|:..|:|.||::::|..:|:::... :|.:.:||.:..::|.....|:..:
  Fly   165 APEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVLLVE-LGVSAQGRPILGVQIAFDNENRTTV 228

  Rat   168 FIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWR 232
            |::.|.||||||:||...:.:.:.|.:.:..:  :.|.....:|:.|.||.|||.||:..|||||
  Fly   229 FVESGIHAREWIAPATATYIIDQLVNSKDSAV--QALARSQRWYIFPTVNPDGYQYTFKGDRMWR 291

  Rat   233 KTRSTMAGSSCLGVDPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLST--I 295
            |.|:..  ..|.|||.||||...|...|||..||...|.||:..||.||:.:.:|||:.:.:  |
  Fly   292 KNRALF--GICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESERI 354

  Rat   296 KAYLTIHSYSQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYPAAGGS 360
            :.::::||||||:::||.:..:..:||.:|..:.|.||.::..:.|..|..|....||||::|||
  Fly   355 RTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGS 419

  Rat   361 DDWSYDQ-GIKYSFTFELR---DTGFFGFLLPESQIRQTCEETMLAVKYI 406
            .||::.| .|..:|::|||   |:... |:|...:|..|..|...:::.|
  Fly   420 KDWAHGQLKIPITFSYELRGPADSEDL-FILSAKEIEPTAAEAFASIQTI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpb1	NP_036665.2	Propep_M14	33..102	CDD:396700	16/68 (24%)
Cpb1	NP_036665.2	M14_CPB	112..410	CDD:349443	104/301 (35%)
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	17/73 (23%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	104/296 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.650