DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpb1 and CG8563

DIOPT Version :9

Sequence 1:	NP_036665.2	Gene:	Cpb1 / 24271	RGDID:	2391	Length:	415	Species:	Rattus norvegicus
Sequence 2:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	129/449 - (28%)
Similarity:	209/449 - (46%)	Gaps:	60/449 - (13%)

- Green bases have known domain annotations that are detailed below.

  Rat     2 LLLLALVSVALAHASEEHFDGNRVYRVSVHGEDHV--NLIQELANTKEIDFW---KPDSATQVKP 61
            |.|:.|..:.:|: :...::|...|.|. ||:::.  .::....|..|:|||   :..|...|.|
  Fly    11 LCLVGLAGLGIAN-NLAGYEGYTKYTVQ-HGDENAFKYMVDLQTNDAELDFWLLTRNSSVLTVSP 73

  Rat    62 LTTVDFHVK-------------AEDVADVE---NFLEEN-EVHYEVLISNVRNALESQFDS---- 105
            .....|...             .|.:|.::   :|.::| :..||          |.|.|.
  Fly    74 RRKTQFEASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEYE----------ECQQDECEQA 128

  Rat   106 -----HTRASGHS-YTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKI---GKTR 161
                 .||..... ::.|.::..:.:::..:|...|.......:|.:.|||::..|.|   .:.|
  Fly   129 ERPRRRTRRQARGFFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVR 193

  Rat   162 PNKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWT 226
            |.:.| :|....|.||||:.....:...|.:.....   ..::|.:::.:::|:||.|||.||.|
  Fly   194 PRRVA-YIQAATHGREWITTQTVLYLAYELLSNLRA---FTRVLQDVEIFLVPLVNPDGYEYTHT 254

  Rat   227 KDRMWRKTRSTMAGSSCLGVDPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNN 291
            .||.|||.|...||.||.|||.||||...|...|||::.|||.|.|.||.||.||.|:..::..|
  Fly   255 TDRFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFN 319

  Rat   292 LSTIKAYLTIHSYSQMMLYPYSY-DYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYP 355
            .:.:|..|.:||:.:.:.|||.| ...:|.....|.::...||.::....||:||.|..|:.:|.
  Fly   320 RNRVKLSLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYTTGTSASILYE 384

  Rat   356 AAGGSDDWSY-DQGIKYSFTFELRDTGFFGFLLPESQIRQTCEETMLA----VKYIANY 409
            |:|..||::| :.||..|:|.||....|.   :|...|...|:||...    :::::.|
  Fly   385 ASGSLDDFAYGNLGIPLSYTLELPGDEFH---VPAHDIIHVCKETFAGFIEFIRHVSLY 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpb1	NP_036665.2	Propep_M14	33..102	CDD:396700	16/90 (18%)
Cpb1	NP_036665.2	M14_CPB	112..410	CDD:349443	100/308 (32%)
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	99/297 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920