DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpb1 and CG2915

DIOPT Version :9

Sequence 1:	NP_036665.2	Gene:	Cpb1 / 24271	RGDID:	2391	Length:	415	Species:	Rattus norvegicus
Sequence 2:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	142/418 - (33%)
Similarity:	213/418 - (50%)	Gaps:	37/418 - (8%)

- Green bases have known domain annotations that are detailed below.

  Rat    17 EEHFDGNRVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTV----DFHVKAEDVADV 77
            :..:|..|:|.|....::.:.|.|:|..       :.||.|.:.....|    ...|.|..|||:
  Fly    52 QARYDNYRIYNVEFENQEQIELFQKLEE-------QSDSLTFIGHAREVGQKLSILVAAHRVADI 109

  Rat    78 ENFLEENEVHYEVLISNV-----RNALESQFDSHTRASGHSYTKYNKWETIEAWIQQVATDNPDL 137
            .:.|:..:|.:.||..|.     ||..|.|.:| ..||...:..:...:||..|:.::....|:.
  Fly   110 ADLLKTYKVKHRVLTYNFQEKIDRNLAEVQPES-IDASQLDWQHFFHLKTIYEWLDKMVEKYPNR 173

  Rat   138 VTQSVIGTTFEGRNMYVLKIGKTRPNKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMK 202
            ||...:|::.:|..:..:|:.....|| ||||:.|.|||||||||...:.:.:.:.  :|:..::
  Fly   174 VTVLDMGSSTQGNAIKGVKLTSNANNK-AIFIESGIHAREWISPAAATYIINQLLT--SQDPKVQ 235

  Rat   203 QLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRSTMAGSSCLGVDPNRNFNAGWCEVGASRSPCS 267
            ||..:.::.:.|.||.|||.||:..||||||.|...  .:|.|||.|||:...|...|:|..|..
  Fly   236 QLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLF--GTCRGVDLNRNYPDHWNSTGSSSDPTR 298

  Rat   268 ETYCGPAPESEKETKALADFIRNNL--STIKAYLTIHSYSQMMLYPYSYDYKLPENYEELNALVK 330
            ..:.||:..||.|||.|.||||.|.  ..||.|:.:||||||:::||.|..:...||::|....|
  Fly   299 YDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGK 363

  Rat   331 GAAKELATLHGTKYTYGPGATTIYPAAGGSDDWSYDQ-GIKYSFTFELRDTGFFG-------FLL 387
            .|:..:...:|..|..|....||||::|||.||::.: ||..::|||||     |       |:|
  Fly   364 KASAAIKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELR-----GPPDSQDLFIL 423

  Rat   388 PESQIRQTCEETMLAVKYIANYVREHLY 415
            |..:|:.|..|...|::.|.....|..|
  Fly   424 PAVEIQPTASEAFTAIRAIVEAAAEKGY 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpb1	NP_036665.2	Propep_M14	33..102	CDD:396700	20/77 (26%)
Cpb1	NP_036665.2	M14_CPB	112..410	CDD:349443	112/307 (36%)
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	137/398 (34%)
		Propep_M14	63..133	CDD:280416	18/76 (24%)
		M14_CP_A-B_like	153..446	CDD:199844	112/302 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.650