DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpb1 and CG17633

DIOPT Version :9

Sequence 1:	NP_036665.2	Gene:	Cpb1 / 24271	RGDID:	2391	Length:	415	Species:	Rattus norvegicus
Sequence 2:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	153/438 - (34%)
Similarity:	233/438 - (53%)	Gaps:	48/438 - (10%)

- Green bases have known domain annotations that are detailed below.

  Rat     1 MLLLLALVSVALAHASEEHFDGNRVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTV 65
            :..|||:|:.|...|....:|..|:|:|:......:.::::|..          |:..:..|..|
  Fly     8 LFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEG----------SSDSIMFLDGV 62

  Rat    66 DFHVKAEDVA------DVENFLE---ENEVHYEVLISNVRNALESQFDSHTRASGHSYTKYNKW- 120
              |:...|:.      .|.:|||   ::|:.||:...:|:.:|: :.|......|.:.|.|| |
  Fly    63 --HLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLD-EIDEKVAIKGRATTAYN-WA 123

  Rat   121 -----ETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKI--------GKTRPNKPAIFIDCG 172
                 :...||:|.:|..||.:||....|.|::||::..:||        ||.   ||.||::.|
  Fly   124 QYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKA---KPGIFLEAG 185

  Rat   173 FHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRST 237
            .||||||:||...:.:.:.:.:..:.|  |:|.:...:||||..|.||||||.|.:|:|||||:.
  Fly   186 IHAREWIAPAAATFIINQLLTSEVENI--KELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTP 248

  Rat   238 MAGSSCLGVDPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIH 302
            .  .||.|.|||||:...|.|||||.|.||:||.||:..||.||.:|:.||......::.||::|
  Fly   249 Y--GSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLH 311

  Rat   303 SYSQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYPAAGGSDDWSY-D 366
            :|||.:||||.:...||:|..:...:...:...:...:||.||.|.....||||||.|.||:| .
  Fly   312 AYSQYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGT 376

  Rat   367 QGIKYSFTFELR--DTGFF-GFLLPESQIRQTCEETMLAVKYIANYVR 411
            |.::.:|.:|||  .|.:. ||.||..||....||.:.::..:|..|:
  Fly   377 QDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVK 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpb1	NP_036665.2	Propep_M14	33..102	CDD:396700	15/77 (19%)
Cpb1	NP_036665.2	M14_CPB	112..410	CDD:349443	125/315 (40%)
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	136/386 (35%)
		Propep_M14	34..105	CDD:280416	16/83 (19%)
		M14_CP_A-B_like	125..423	CDD:199844	121/304 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351647
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3014
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.700