DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpb1 and CG7025

DIOPT Version :9

Sequence 1:	NP_036665.2	Gene:	Cpb1 / 24271	RGDID:	2391	Length:	415	Species:	Rattus norvegicus
Sequence 2:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	415	Identity:	144/415 - (34%)
Similarity:	237/415 - (57%)	Gaps:	26/415 - (6%)

- Green bases have known domain annotations that are detailed below.

  Rat     3 LLLALVSVA--LAHASEE--HFDGNRVYRVSVHGEDHVNLIQELANTKE-IDFWKPDSATQVKPL 62
            ::||||.:|  .:...:|  .:|...||:|....:...:::::||..:| ...|.     :.|.
  Fly     8 IVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRLWH-----EAKD- 66

  Rat    63 TTVDFHVKAEDVA--DVENFLEENEVHYEVLISNVRNALESQFDSHTRAS---GHSYTKYNKWET 122
               :.|:.....|  ::|..:::..|..|:.||||:..::|:..::.:||   ...:||||....
  Fly    67 ---ELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFGWTKYNSLAE 128

  Rat   123 IEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGKTRPNKPAIFIDCGFHAREWISPAFCQWF 187
            |.||:..:....|.:....::|.::|||.:..:|| ..:.|.|.:.|:...||||||:.|...|.
  Fly   129 IYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKI-SYKSNNPGVLIESNIHAREWITSATATWL 192

  Rat   188 VREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRSTMAGSSCLGVDPNRNF 252
            :.|.: |...|: ::.|.:..|:|::||:|:||:|||..|||||||||.....|||:|.|||||:
  Fly   193 INEFL-TSTDEL-VRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNY 255

  Rat   253 NAGWCE-VGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIHSYSQMMLYPYSY-D 315
            ::.|.| .|||.:||:|.|.||.|.||.|.:|:::|:.:....|...|..|||||::|.||.: .
  Fly   256 DSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGHTK 320

  Rat   316 YKLPENYEELNALVKGAAKELATL-HGTKYTYGPGATTIYPAAGGSDDWSY-DQGIKYSFTFELR 378
            .:.|.|::::..:.|.....:.:| :||.|.||..|..:|||:|.:.||:| :||::.|:|.|.|
  Fly   321 EEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIEFR 385

  Rat   379 DTGFFGFLLPESQIRQTCEETMLAV 403
            |||.:||:||...|....||.::.:
  Fly   386 DTGRYGFILPPVHIIPNAEEALIGI 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpb1	NP_036665.2	Propep_M14	33..102	CDD:396700	14/71 (20%)
Cpb1	NP_036665.2	M14_CPB	112..410	CDD:349443	117/296 (40%)
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	15/75 (20%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	115/291 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3014
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.700