back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cpa1 and CG2915

DIOPT Version :9

Sequence 1:	NP_058694.2	Gene:	Cpa1 / 24269	RGDID:	2388	Length:	419	Species:	Rattus norvegicus
Sequence 2:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster

Alignment Length:	448	Identity:	126/448 - (28%)
Similarity:	232/448 - (51%)	Gaps:	46/448 - (10%)

- Green bases have known domain annotations that are detailed below.

  Rat     4 LLILSLLLEA--------VC---------GN----ENFVGHQVLRISAADEAQVQKVKELEDLEH 47
            |:||.:.:.|        :|         ||    ..:..:::..:...::.|::..::||: :.
  Fly    18 LVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEE-QS 81

  Rat    48 LQLDFWRDAARAGIPIDVRVPFPSIQSVKAFLEYHGISYEIMIEDVQLLLDEEKQQMSAFQARAL 112
            ..|.|...|...|..:.:.|....:..:...|:.:.:.:.::..:.|..:|   :.::..|..::
  Fly    82 DSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKID---RNLAEVQPESI 143

  Rat   113 STDSFNYATYHTLDEIYEFMDLLVAEHPQLVSKIQIGNTFEGRPIHVLKFSTGGTNRPAIWIDTG 177
            .....::..:..|..|||::|.:|.::|..|:.:.:|::.:|..|..:|. |...|..||:|::|
  Fly   144 DASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKL-TSNANNKAIFIESG 207

  Rat   178 IHSREWVTQASGVWFAKKITKDYGQDPTFTAVLDNMDIFLEIVTNPDGFAYTHKTNRMWRKTRSH 242
            ||:|||::.|:..:...::..  .|||....:..:.:..:....||||:.||.:.:|||||.|.
  Fly   208 IHAREWISPAAATYIINQLLT--SQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQ- 269

  Rat   243 TQGSLCVGVDPNRNWDAGFGMAGASSNPCSETYRGKFPNSEVEVKSIVDFVTSHG---NIKAFIS 304
             ....|.|||.|||:...:...|:||:|....:.|....||:|.|.::||:.::.   .||.:|:
  Fly   270 -LFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIA 333

  Rat   305 IHSYSQLLLYPYGYTSEPAPDQAELDQLAKSAVTALTSLHGTKFKYGSIIDTIYQASGSTIDWTY 369
            :|||||:|::|||||.|...:..:|.:..|.|..|:.:.:|..:..||:.:|||.:||.::||.:
  Fly   334 LHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENGRDYVSGSLFETIYPSSGGSMDWAH 398

  Rat   370 SQ-GIKYSFTFELRDTGLRG-------FLLPASQIIPTAEETWLALLTIMDHTVKHPY 419
            |: ||..::|||     |||       |:|||.:|.|||.|.:.|:..|::...:..|
  Fly   399 SEAGIPIAYTFE-----LRGPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEKGY 451

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.