DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cat and Cat

DIOPT Version :9

Sequence 1:	NP_036652.1	Gene:	Cat / 24248	RGDID:	2279	Length:	527	Species:	Rattus norvegicus
Sequence 2:	NP_536731.1	Gene:	Cat / 40048	FlyBaseID:	FBgn0000261	Length:	506	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	330/503 - (65%)
Similarity:	397/503 - (78%)	Gaps:	4/503 - (0%)

- Green bases have known domain annotations that are detailed below.

  Rat     5 RDPASDQMKQWKEQRAPQKPDVLTTGGGNPIGDKLNIMTAGPRGPLLVQDVVFTDEMAHFDRERI 69
            ||.||:|:..:|..:. ..|..:|||.|.|||.|....|.|||||:|:|||.|.|||:|||||||
  Fly     4 RDAASNQLIDYKNSQT-VSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERI 67

  Rat    70 PERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAV 134
            |||||||||||||||||||||||:|..||:|:.:.||||:|||||||.||||||||.||||||||
  Fly    68 PERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAV 132

  Rat   135 KFYTEDGNWDLVGNNTPIFFIRDAMLFPSFIHSQKRNPQTHLKDPDMVWDFWSLCPESLHQVTFL 199
            |||||||.|||||||||:|||||.:|||||||:||||||||||||||.|||.:|.|||.|||..|
  Fly   133 KFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVCIL 197

  Rat   200 FSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLPVEEAGRLAQEDPDYGLRD 264
            |||||.|||:.||||||||||||:||.||.:|.|||:|||||||||.|:.|.:||..||||.:||
  Fly   198 FSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRD 262

  Rat   265 LFNAIASGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPANYFAEV 329
            |:|.|.:..:||||.||||||:::|:.|.:||||:||||..|:||||||||:||:|||.||||||
  Fly   263 LYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEV 327

  Rat   330 EQMAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCM 394
            ||:||.|:::.||:||||||||.||||:|.||||||||||||||||||||:.::.|:||||.|.:
  Fly   328 EQIAFSPAHLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDGAMNV 392

  Rat   395 HDNQGGAPNYYPNSFSAPEQ--QGSALEHHSQCSADVKRFNSAN-EDNVTQVRTFYTKVLNEEER 456
            .|||.|||||:||||:.|::  :..||......:.||.|::|.: |||..||..|:..||::..:
  Fly   393 TDNQDGAPNYFPNSFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDKCAK 457

  Rat   457 KRLCENIANHLKDAQLFIQRKAVKNFTDVHPDYGARVQALLDQYNSQK 504
            |||.:|||.||.:|..|:|.:||||||.||.|:|..:...|:...|.|
  Fly   458 KRLVQNIAGHLSNASQFLQERAVKNFTQVHADFGRMLTEELNLAKSSK 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cat	NP_036652.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34		11/28 (39%)
Cat	NP_036652.1	catalase_clade_3	68..497	CDD:163712	293/431 (68%)
Cat	NP_536731.1	KatE	10..505	CDD:223824	326/497 (66%)
Cat	NP_536731.1	catalase_clade_3	66..498	CDD:163712	295/434 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354461
Domainoid	1	1.000	620	1.000	Domainoid score	I171
eggNOG	1	0.900	-	-		E1_COG0753
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	691	1.000	Inparanoid score	I659
OMA	1	1.010	-	-		QHG62736
OrthoDB	1	1.010	-	-		D172396at33208
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		otm44502
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	LDO	PTHR11465
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770