DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ascl2 and HLH4C

DIOPT Version :9

Sequence 1:NP_113691.1 Gene:Ascl2 / 24209 RGDID:2159 Length:260 Species:Rattus norvegicus
Sequence 2:NP_001259243.1 Gene:HLH4C / 31397 FlyBaseID:FBgn0011277 Length:191 Species:Drosophila melanogaster


Alignment Length:192 Identity:52/192 - (27%)
Similarity:71/192 - (36%) Gaps:68/192 - (35%)


- Green bases have known domain annotations that are detailed below.


  Rat    22 RESCSSALPEAREGANVHFPPHPVPREHFSCGAPKPVAGAPALNASLMDGGALPRLVPTSSGVAG 86
            |.:|.:|...|...     ||.|.||...:     |:|   .|:.|.:.|               
  Fly    57 RMACETAAQPAPPP-----PPTPAPRRRTT-----PIA---HLDPSELVG--------------- 93

  Rat    87 ACTARRRPPSPELLRCSRRRRSGATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGGAN 151
                        |.|..||||..||....::.|.     |||.||:..|:.|..||:.:|....:
  Fly    94 ------------LSREERRRRRRATLKYRTAHAT-----RERIRVEAFNVSFAELRKLLPTLPPD 141

  Rat   152 KKLSKVETLRSAVEYIRALQRLLAEHDAVRAALSGGLLTPATRPSDVCTQPSASPASASLSC 213
            |||||:|.|:.|:.||..|..:|                  ..|.|     ||..:|.:.||
  Fly   142 KKLSKIEILKLAICYIAYLNHVL------------------ETPXD-----SAGASSFATSC 180

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ascl2NP_113691.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 85..126 9/40 (23%)
HLH 134..176 CDD:197674 17/41 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..239 7/23 (30%)
HLH4CNP_001259243.1 HLH 108..165 CDD:238036 23/79 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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