Protein Alignment Akr1b1 and Akr1B

DIOPT Version :9

• Sequence 1: NP_036630.1
• Gene: Akr1b1 / 24192
• RGDID: 2092
• Length: 316
• Species: Rattus norvegicus
• Sequence 2: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 184/307 - (59%)
• Similarity: 227/307 - (73%)
• Gaps: 2/307 - (0%)

  Rat     9 NGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDL 73
            :|.::|.:||||:.||.||||||||||||.||||||||.|||||.|||..::.|:||.||||:||
  Fly    44 DGNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDL 108

  Rat    74 FIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDF 138
            ||.||||.|||...:||.|.:.|||.|:|.||||||||||.|:|.|.|.||.|..|..:.|..|:
  Fly   109 FITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDY 173

  Rat   139 VDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCK 203
            ||||.|||:||:|||||:|||||||..||||:|....:  .|..|||||||||||:|||::|..|
  Fly   174 VDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSK 236

  Rat   204 GIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPA 268
            .|.:|||||||||:|||||..||.:||:.:|||||||..||..|:|||:.:||..:|||||||..
  Fly   237 DITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKD 301

  Rat   269 RIAENFKVFDFELSNEDMATLLSYNRNWRVCALMSCAKHKDYPFHAE 315
            ||..||:||||||:.|::..:.|:..|.|:..|::...|..:||..:
  Fly   302 RIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKD 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1b1	NP_036630.1	ARA1	1..297	CDD:223729	179/287 (62%)
		Tas	8..289	CDD:223739	177/279 (63%)
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	176/273 (64%)
		Tas	45..>248	CDD:223739	132/204 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348824
Domainoid	1	1.000	356	1.000	Domainoid score	I948
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2032
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm45342
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770