Protein Alignment Atp8b4 and CG33298

DIOPT Version :9

• Sequence 1: NP_001074413.2
• Gene: Atp8b4 / 241633
• MGIID: 1859664
• Length: 1194
• Species: Mus musculus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1339
• Identity: 404/1339 - (30%)
• Similarity: 646/1339 - (48%)
• Gaps: 271/1339 - (20%)

Mouse    17 KANDRDYNEKFQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTT 81
            |...||: ...|:..|:|.|:||.:|:|:|.||.||..||||.||:|:::|..:||||:......
  Fly   239 KTPKRDH-PNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVA 302

Mouse    82 IVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVL--INSKLQNEKWMNVKVGDIIKLENNQF 144
            ::|::.|:.:|||||..:|..|..||.::||...:|.  ...:.:..||..::||||:.|.||:.
  Fly   303 MIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNET 367

Mouse   145 VAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKL 209
            |.||:|||.:|:|.|:||::|.:||||||||.|:.:....|: ..|...::|...|..:||..||
  Fly   368 VPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEM-QSIFVPSKFVSRVEADAPTTKL 431

Mouse   210 DRFSGVLSWKDSKHA-LSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRL 273
            .||.|.|.....:.. :|.:.::||...|:||.:..|:|::||.:||.|.|:...::||:.:::.
  Fly   432 YRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQ 496

Mouse   274 MNTLVLWIFGFLVCLGIILAVG-----SSILESEVGDQFRTPPFWREGEKSFLFSGFLTFWSYVI 333
            ||..|:|....|:.|.::.|:|     ||.....|       |:....:.:........||:|::
  Fly   497 MNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPV-------PYLPPNKLTANMESMWIFWTYIV 554

Mouse   334 ILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTL 398
            ||..::|:||||::|:.::...:.|:.:..::.|......|.|...:.||||||::||:||||||
  Fly   555 ILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTL 619

Mouse   399 TQNIMTFKKCSINGRVYAGEVLDDPIQKKEITKEKEATDFSSKSKSEKTLHFFDQSLMESIELGD 463
            |:|.|.|::|.:||..|     :.|..:.|....|..........::..     .|.|..:..|.
  Fly   620 TENKMIFRRCVVNGSDY-----NHPPSELEKIYSKPGAPAPPLIPNDNL-----NSDMAQLTQGT 674

Mouse   464 ------PKVHEFLRLLALCHTVM------------------------------------------ 480
                  .::.|||.:||:|:||:
  Fly   675 YLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASST 739

Mouse   481 ----------------------------------------------------------------- 480
                                                                             
  Fly   740 STTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAES 804

Mouse   481 ---SEENSA-------------------------------------------------------- 486
               ||..|.
  Fly   805 SPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRT 869

Mouse   487 --GQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIE--ELGTPVTYQLLAFLDFNNIRKRMS 547
              |:.:|:.:||||.|||.||.::.....:|:|..|.:.  ..|....|::|..|.|::.||.||
  Fly   870 ADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMS 934

Mouse   548 VIVRN-PEGRIKLYSKGADTILFEKLHPSNED-----LQSLTSDHLSEFAGEGLRTLAIAYRELD 606
            ::||. ....|.||:||||:.:...|.|.:.:     |:..|...|..:|.||||.|.:|.|.|:
  Fly   935 IVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLN 999

Mouse   607 DKYFKMWQKMLEDANSATLERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIK 671
            ...:..|....::...:...|:.|:...:.::|.:|.|||||.:||:||:||.|||.||..|.|.
  Fly  1000 SADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGIS 1064

Mouse   672 IWILTGDKQETAINIGYACNVLTDAMDALFVITGNTAGEVREELRKAKENLLGQSTSFSNGHA-V 735
            :|:|||||.||||||.|:..:.|..|: |..:|..:.......:.....::....|:.:.|:. .
  Fly  1065 VWVLTGDKPETAINIAYSAKLFTQQME-LIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQS 1128

Mouse   736 YDNKQRLGLDAGAGEAVTGEYALVINGHSLAHALE--SDVENDLLELACVCKTVVCCRVTPLQKA 798
            ...|||               |||::|.:|...|:  |.:....|.|:..|.:|:|||.||||||
  Fly  1129 LRKKQR---------------ALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKA 1178

Mouse   799 QVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVH 863
            .:|::||:..|..||||||||||||||:.|.:|:|||||||:|||:|:|:.|.:||||:||||.|
  Fly  1179 YLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAH 1243

Mouse   864 GRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGMFD 928
            |.|.|.|:.:.:.||||||.||..:.||:..:||||.|.:.||.::.|:|:::||||.||:|::|
  Fly  1244 GYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYD 1308

Mouse   929 QDINEQNSMDYPQLYEPGQLNLLFNKRRFFICVAHGIYTSLALFFIPYGAFYNVAAEDGQHIADL 993
            :.:.|...:..|.||:.|:|.:.:....|::.:...:|.||.:||:...|:   |..|    ..:
  Fly  1309 KRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAY---AESD----VGI 1366

Mouse   994 QSFAVTVATSLVIVVSIQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGV----FGIFPRH- 1053
            ..|..|:..|.:....:..|::...|||::.:.|..|:.:::  |.|:..|.|    ||:...:
  Fly  1367 WEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFY--LFAIVYDSVCMNCFGVRSSYW 1429

Mouse  1054 --FPFVGNARHSLSQKFVWLVVLLTAVTSVMPVVVVRFLKMYLYPSLSDQIRRWQKAQRKKRPLR 1116
              |....:|.|       |||::|:.|.:|:|.:::..:::.|.|..|.::           .|:
  Fly  1430 VIFVCFASAVH-------WLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKV-----------ILQ 1476

Mouse  1117 SRRPQTR---------RSSSRRSGYAFAHQEGYGELITS 1146
            |:|.::|         ||:|..|.|.........::||:
  Fly  1477 SKRERSRGEALLVTWSRSTSASSIYRITDYGSKNQIITT 1515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp8b4	NP_001074413.2	P-type_ATPase_APLT_Dnf-like	31..975	CDD:319770	358/1136 (32%)
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	25/49 (51%)
		ATPase-Plipid	250..1473	CDD:273734	389/1272 (31%)
		E1-E2_ATPase	302..>394	CDD:278548	37/91 (41%)
		Cation_ATPase	<880..965	CDD:289987	32/84 (38%)
		HAD_like	<1177..1240	CDD:304363	40/62 (65%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	85/260 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830