Protein Alignment Slc5a12 and CG31262

DIOPT Version :9

• Sequence 1: NP_001003915.1
• Gene: Slc5a12 / 241612
• MGIID: 2138890
• Length: 623
• Species: Mus musculus
• Sequence 2: NP_001138069.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Alignment Length: 577
• Identity: 182/577 - (31%)
• Similarity: 297/577 - (51%)
• Gaps: 48/577 - (8%)

Mouse     6 FEAWDYVVFAGLFVISSGIGVFF-AIKER---KKTTSR-------------EFLVGGRQMSFGPV 53
            |...||:|...:.::|:|.|::| |:|::   ||:.|.             |:|:|.|.|...||
  Fly     6 FGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPV 70

Mouse    54 ALSLTASFMSAVTVLGTPAEVYRFGASFFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLR 118
            :::|    ....:::|||:|:|.:|..::|.:::.:......|.::|||:....|.|.||||.||
  Fly    71 SITL----YRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLR 131

Mouse   119 FNKPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVW 183
            ||..:|..|:.:|:...:.|...:||.|||:|:||:|.|.........:.|..|..:|||||||.
  Fly   132 FNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMGGLKAVVH 196

Mouse   184 TDAFQMVVMIVGFLTVLIQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFT 248
            ||.:|:.||.:..:.|......:..|...|.:.|..|.||.:.:.:..|..|||.|::.|||...
  Fly   197 TDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGGFSF 261

Mouse   249 WLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVIS 313
            |..|....|..:||.:|..:.|.::.|.:...:|:.|.:|...|.||:::|.:|||||.::|:|.
  Fly   262 WTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDPRSAGMIL 326

Mouse   314 APDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFP-HLSDKLS 377
            ..|||:|.||::....:.|:||||:|..|...||::::..|.::.|..||.|:..|. ..|::.|
  Fly   327 NDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQS 391

Mouse   378 TWISKGLCILFGIMCTSMAVVASLMGSVVQ-APGIVSQERAITGSFQRNLASVCYGVSI------ 435
            |.:.| .||:|      ..::|.|:..::| ..||:|    :..|.....|...:||..
  Fly   392 TILIK-TCIIF------QGILAFLIVFLLQHLRGILS----VCNSISSITAGTSFGVFTLGMLFP 445

Mouse   436 WKLIMGALGGLLTGITLSFWVAIGSFIYPAP-ESKTLPLPLSTEHCVELNITTTVAPQISSRPVL 499
            |...:|...|.|:.:.|:.|::.||.|..|. :.|:..||:|.:.||. |:|....|.:....|.
  Fly   446 WANTIGTAVGGLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVG-NVTLPEDPWVDQDQVF 509

Mouse   500 ADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLF----CF 552
              ..|.|||.:.|.:|.:..:..|.::|.:|.....|.:...||.||.:.|    ||
  Fly   510 --PLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECF 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a12	NP_001003915.1	SLC5-6-like_sbd	3..531	CDD:294310	173/550 (31%)
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	169/530 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836563
Domainoid	1	1.000	46	1.000	Domainoid score	I12033
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.840