Protein Alignment FTSJ1 and Trm7-32

DIOPT Version :10

• Sequence 1: NP_001428126.1
• Gene: FTSJ1 / 24140
• HGNCID: 13254
• Length: 337
• Species: Homo sapiens
• Sequence 2: NP_650590.1
• Gene: Trm7-32 / 42056
• FlyBaseID: FBgn0038471
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 154/293 - (52%)
• Similarity: 192/293 - (65%)
• Gaps: 43/293 - (14%)

Human     1 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKI-- 63
            ||:|||||||:|||.||:.|||||||||||.:|:.:.:..||.|||||||||||||||||:|:
  Fly     1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLSRKLYD 65

Human    64 -----GGQGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGC-PADLVVCDGAPDVT 122
                 ..:.:..::|||||||||:.|::|:|||||:.|||:.||.||.|. .|.|||||||||||
  Fly    66 TCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVT 130

Human   123 GLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRN 187
            |:|::|||||.|||:|||:|||.||:.||.||||||:|...:||.||:|:||......||.|||.
  Fly   131 GVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSSRP 195

Human   188 SSIEAFAVCQGYDPPEGFIPDLSKPLLDHSYDPDFNQLDGPT-----RIIVPFVTCGDLSS---- 243
            ||||||.||..:..|||:||.:..|..|     |...|...|     |.:|||:.||||:.
  Fly   196 SSIEAFVVCSDFCLPEGYIPQVINPARD-----DIRLLAQKTGSEVNRRLVPFIACGDLNGLSDP 255

Human   244 ------------------YDS---DRSYPLDLE 255
                              ||:   |.||||:.:
  Fly   256 EEGKTSSSDESKSNLEYVYDAVMDDASYPLEFK 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FTSJ1	NP_001428126.1	Required for binding to WDR6. /evidence=ECO:0000269|PubMed:32558197	221..240		8/23 (35%)
Trm7-32	NP_650590.1	RlmE	1..207	CDD:440062	129/205 (63%)