| Sequence 1: | NP_001380015.1 | Gene: | prp-19 / 24104882 | WormBaseID: | WBGene00020423 | Length: | 492 | Species: | Caenorhabditis elegans |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055317.1 | Gene: | PRPF19 / 27339 | HGNCID: | 17896 | Length: | 504 | Species: | Homo sapiens |
| Alignment Length: | 505 | Identity: | 261/505 - (51%) |
|---|---|---|---|
| Similarity: | 349/505 - (69%) | Gaps: | 16/505 - (3%) |
- Green bases have known domain annotations that are detailed below.
|
Worm 1 MSFVCGISGELTEDPVVSQVSGHIFDRRLIVKFIAENGTDPISHGELSEDQLVSLKSGGTGSAPR 65
Worm 66 NVSGTSIPSLLKMLQDEWDTVMLNSFSLRQQLQIARQELSHSLYQHDAACRVISRLSKELTAARE 130
Worm 131 ALSTLKPHTSAKVDDDVSIDESE-----------DQQGLSEAILAKLEEKSKSLTAERKQRGKNL 184
Worm 185 PEGLAKTEELAELKQTASHTGIHSTGTPGITALDI---KGNLSLTGGIDKTVVLYDYEKEQVMQT 246
Worm 247 FKGHNKKINAVVLHPDNITAISASADSHIRVWSATDSSSKAIIDVHQAPVTDISLNASGDYILSA 311
Worm 312 SDDSYWAFSDIRSGKSLCKVSVEPGSQIAVHSIEFHPDGLIFGTGAADAVVKIWDLKNQTVAAAF 376
Worm 377 PGHTAAVRSIAFSENGYYLATGSEDGEVKLWDLRKLKNLKTFANEEKQPINSLSFDMTGTFLGIG 441
Worm 442 GQKVQVLHVKSWSEVVSLSDHSGPVTGVRFGENARSLVTCSLDKSLRVFS 491 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| prp-19 | NP_001380015.1 | RING-Ubox_PRP19 | 4..56 | CDD:319570 | 30/51 (59%) |
| Prp19 | 70..134 | CDD:400774 | 51/63 (81%) | ||
| SMC_prok_B | <74..>201 | CDD:274008 | 74/137 (54%) | ||
| WD40 | 213..491 | CDD:238121 | 140/280 (50%) | ||
| WD40 repeat | 255..291 | CDD:293791 | 13/35 (37%) | ||
| WD40 repeat | 296..335 | CDD:293791 | 24/38 (63%) | ||
| WD40 repeat | 342..377 | CDD:293791 | 20/34 (59%) | ||
| WD40 repeat | 383..418 | CDD:293791 | 26/34 (76%) | ||
| WD40 repeat | 456..490 | CDD:293791 | 12/33 (36%) | ||
| PRPF19 | NP_055317.1 | RING-Ubox_PRP19 | 4..56 | CDD:319570 | 30/51 (59%) |
| May mediate interaction with PSMC5. /evidence=ECO:0000250|UniProtKB:Q99KP6 | 68..223 | 84/154 (55%) | |||
| Prp19 | 69..133 | CDD:400774 | 51/63 (81%) | ||
| WD 1 | 219..259 | 18/39 (46%) | |||
| WD40 | 223..503 | CDD:238121 | 140/280 (50%) | ||
| WD40 repeat | 224..262 | CDD:293791 | 17/37 (46%) | ||
| WD 2 | 262..301 | 17/38 (45%) | |||
| WD40 repeat | 268..304 | CDD:293791 | 13/35 (37%) | ||
| WD 3 | 304..345 | 24/40 (60%) | |||
| WD40 repeat | 309..344 | CDD:293791 | 22/34 (65%) | ||
| WD 4 | 348..387 | 20/39 (51%) | |||
| WD40 repeat | 354..389 | CDD:293791 | 20/34 (59%) | ||
| WD 5 | 390..429 | 27/38 (71%) | |||
| WD40 repeat | 395..431 | CDD:293791 | 27/35 (77%) | ||
| WD 6 | 433..472 | 14/38 (37%) | |||
| WD40 repeat | 438..464 | CDD:293791 | 11/25 (44%) | ||
| WD 7 | 473..503 | 12/29 (41%) | |||
| WD40 repeat | 476..502 | CDD:293791 | 10/25 (40%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C161471739 | |
| Domainoid | 1 | 1.000 | 109 | 1.000 | Domainoid score | I4417 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0289 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 517 | 1.000 | Inparanoid score | I756 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1589 |
| OMA | 1 | 1.010 | - | - | QHG54686 | |
| OrthoDB | 1 | 1.010 | - | - | D1049599at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003405 | |
| OrthoInspector | 1 | 1.000 | - | - | oto23450 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102145 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR43995 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R276 |
| SonicParanoid | 1 | 1.000 | - | - | X2757 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.790 | |||||