Protein Alignment Slco2a1 and Oatp58Db

DIOPT Version :9

• Sequence 1: NP_201571.2
• Gene: Slco2a1 / 24059
• MGIID: 1346021
• Length: 643
• Species: Mus musculus
• Sequence 2: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 166/648 - (25%)
• Similarity: 299/648 - (46%)
• Gaps: 86/648 - (13%)

Mouse    23 CSRSVFN--------NIKVFVLCHGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEI 79
            |..|:|.        ...:||:.:|:......:...||..::||:||||.:.:..||||:..|:|
  Fly    35 CGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDI 99

Mouse    80 SNAILIIFVSYFGSRVNRPRMIGIGGLLLAAGAFVLTLPHFLSEPYQYA---STTAGNSSHF--Q 139
            |......|:||:.||.:|||.:.:|.:::|....::..||....|.:.|   :...|.|..|  .
  Fly   100 STVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGAS 164

Mouse   140 TDLCQKHLPGLLPSKCHSTVPDTQKETSSMWSLMV--VAQLLAGVGTVPIQPFGISYVDDFAEPT 202
            .::.:|:     .|.||....:..:.......:::  :||.:.|:|.......|:||:||.:..:
  Fly   165 LNITEKN-----DSLCHEKNSNCLERAGDYTPIVLFFIAQFIGGIGCSLFYAPGLSYMDDNSASS 224

Mouse   203 NSPLYISILFAIAVFGPAFGYLLGSVMLRIFVDYGRVDTATVNLSPGDPRWIGAWWLGLLISSGF 267
            .:|..:|....:.:.|||.|:.:.|:.||:::|..:....|.|    ||||:||||:|.::.:..
  Fly   225 KTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDPFKKPLITTN----DPRWMGAWWIGWILLTFI 285

Mouse   268 LIVTSLPFFFFPRAMSRGAERSVIAEETMKMEED-----KSRGSLMDFIKRFPRIFLRLLMNPLF 327
            |.::::....||:.|.|...|.:.|:.    |||     :|...::|.:|       ||..|.::
  Fly   286 LTISAVFVGMFPKEMPRAKARRLKADG----EEDIPLAGRSFQDMLDSLK-------RLASNKVY 339

Mouse   328 MLVVLSQCTFSSVIAGLSTFLNKFLEKQYDASAAYANLLIGAVNLPAAALGMLFGGILMKRFVFP 392
            :..:|:...:.........|..|::|.||..||:.:.:..|...|..:|.|:|..|.::.::
  Fly   340 VYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKY--- 401

Mouse   393 LQTIPRVAAT------IMTISIILCAPLFFMGCSTPAVAEVYPPSTPSSIHPQPPACRRDCLCPD 451
             :...|..|.      .:|::.:||..|  :||.....|      ...||.|...:|...|:|..
  Fly   402 -KPSARAMAAWNFVVDYLTVAGMLCYVL--VGCDESDRA------NSLSIVPTGDSCSASCVCEY 457

Mouse   452 SVFHPVCGDNGVEYLSPCHAGCSSLNVSSAASKQPIYLNCSCVTGGSAS---------------- 500
            ..:.|||....:.::|.|||||:...::...  :.||..|.|:  |:.|
  Fly   458 VYYAPVCSPENITFISACHAGCTDKAINELG--KTIYTGCRCM--GNVSSIISLSNVTSLASQSQ 518

Mouse   501 -AKTGSCPTSCAQLLLPSIFLISFVALIACVSHNPLYMMVLRVVNQDEKSFAIGVQFLLMRLLAW 564
             |..|:||..|.:..|..:.::.|:..:.....:...::.||.|...:|:|::|...::..:||:
  Fly   519 IAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAF 583

Mouse   565 LPSPSLYGLLIDSSCIRWNYLCSGRRGACAYYDNDALRNRYLGLQVIYKVLGTLLLFFISWRV 627
            :|||.::|.::||.|:.|...||. :|.|..||..:||      ..:..|..:|:.....|.:
  Fly   584 IPSPIVFGWMLDSYCLVWGKTCSS-KGNCWIYDTKSLR------YTMNLVCASLIFLGSFWNI 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slco2a1	NP_201571.2	oat	1..629	CDD:273279	166/648 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		MFS	<166..>425	CDD:119392	68/271 (25%)
		KAZAL_SLC21	441..494	CDD:238650	15/52 (29%)
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	158/602 (26%)
		MFS	55..>410	CDD:119392	99/378 (26%)
		KAZAL_SLC21	447..499	CDD:238650	16/55 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850