Protein Alignment Slco2a1 and Oatp58Da

DIOPT Version :9

• Sequence 1: NP_201571.2
• Gene: Slco2a1 / 24059
• MGIID: 1346021
• Length: 643
• Species: Mus musculus
• Sequence 2: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 177/636 - (27%)
• Similarity: 298/636 - (46%)
• Gaps: 66/636 - (10%)

Mouse    33 VFVLCHGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSYFGSRVNR 97
            ::|:.:||......:..|||..::||:|||:.:.:..||:||..|:||..:....:.|:....:|
  Fly    67 MYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHR 131

Mouse    98 PRMIGIGGLLLAAGAFVLTLPHF----------LSEPYQYASTTAGNSSHFQTDLCQKHLPGLLP 152
            ||.:|||.|.:.|...:.:..||          |:..:...:.|..|... ...|||....|.:.
  Fly   132 PRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQER-DKKLCQPTAGGCVQ 195

Mouse   153 SKCHSTVPDTQKETSSMWSLMVVAQLLAGVGTVPIQPFGISYVDDFAEPTNSPLYISILFAIAVF 217
            .:....||..         .:..|||::|||.......||:|:||......:|..:|:...:.:.
  Fly   196 EEVGLWVPQV---------FLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRML 251

Mouse   218 GPAFGYLLGSVMLRIFVDYGRVDTATVNLSPGDPRWIGAWWLGLLISSGFLIVTSLPFFFFPRAM 282
            |||.||.|.:|.||::::    .|....:...||||:||||||.|:.:...:|:::..|.||:.:
  Fly   252 GPAIGYSLAAVCLRLYIE----PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQL 312

Mouse   283 SRGAERSVIAEETMKMEEDK-----SRGSLMDFIKRFPRIFLRLLMNPLFMLVVLSQCTFSSVIA 342
            ....:|.:    .:|.:|.|     :..||.|.:|...    :|..|.:::...::...:.....
  Fly   313 PSARKRRL----QLKQDERKQSLPLNERSLADMMKTVK----KLSKNKVYVYNTMASILYFFGYM 369

Mouse   343 GLSTFLNKFLEKQYDASAAYANLLIGAVNLPAAALGMLFGGILMKRFVFPLQTIPRVAATI--MT 405
            ....|..|::|.||..|||.|.:..|.|.|..:|.|:|..|.::.::....:.:....|.:  :|
  Fly   370 VYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVT 434

Mouse   406 ISIILCAPLFFMGC-STPAVAEVYPPSTPSSIHPQPPACRRDCLCPDSVFHPVCGDNGVEYLSPC 469
            ::.|||  ...:|| .:..:..:...|..:|       |...|.|....:.|||..:.:.::|.|
  Fly   435 VAGILC--YVAIGCEGSDRLNTLTTLSAGNS-------CSASCHCDYVHYAPVCSADNITFISAC 490

Mouse   470 HAGCSSLNVSSAASKQPIYLNCSCVTGGSAS---------AKTGSCPTSCAQLLLPSIFLISFVA 525
            |||||..  :..|..:.||..|.|:  ||:|         |..|:||..|....|..:.::.|:.
  Fly   491 HAGCSER--TKDALGRTIYTGCECL--GSSSLNSEPESQFAVDGTCPVDCFNEFLIFLGVMCFLK 551

Mouse   526 LIACVSHNPLYMMVLRVVNQDEKSFAIGVQFLLMRLLAWLPSPSLYGLLIDSSCIRWNYLCSGRR 590
            |:...|.:...::.||.:..|||:||:|:..:...||.::|||..:|.|||:.|:.|...|| .:
  Fly   552 LVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCS-NK 615

Mouse   591 GACAYYDNDALRNRYLGLQVIYKV-LGTLLLFFISWRVKKNREYSLQENAS 640
            |.|..||..::|.. |.|...:.: ||..|...: |...||.:...:|.:|
  Fly   616 GNCWLYDTKSMRYA-LNLSAAFFIFLGGFLNIAV-WYHAKNLKIFDEEESS 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slco2a1	NP_201571.2	oat	1..629	CDD:273279	173/623 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		MFS	<166..>425	CDD:119392	71/266 (27%)
		KAZAL_SLC21	441..494	CDD:238650	17/52 (33%)
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	166/594 (28%)
		MFS	69..>425	CDD:119392	102/377 (27%)
		KAZAL_SLC21	462..514	CDD:238650	19/62 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835531
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750