DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf13 and SPAC57A7.09

DIOPT Version :9

Sequence 1:	NP_001106884.1	Gene:	Rnf13 / 24017	MGIID:	1346341	Length:	381	Species:	Mus musculus
Sequence 2:	NP_593372.1	Gene:	SPAC57A7.09 / 2542187	PomBaseID:	SPAC57A7.09	Length:	372	Species:	Schizosaccharomyces pombe

Alignment Length:	300	Identity:	77/300 - (25%)
Similarity:	115/300 - (38%)	Gaps:	80/300 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse    33 EADILAYNFENASQTFEDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPLKDNSSGTFIVLI 97
            |.||:.|:.|...|                  |.:  :|||....:.......||.:...|: |:
pombe   104 ENDIIDYDIEYIEQ------------------KSY--SSKPSARVQKDDGGESKDEAILDFL-LV 147

Mouse    98 RRLDCNFDIKVLNAQRAGYKAAIV---HNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLK 159
            :|..|.:..|.|.|||.|:|..||   .:..|..|..|.:.|.....|:.|||:|:..||.|.|.
pombe   148 QRGKCTYFDKALEAQRLGFKGVIVGDNRSPSSFRLHYMVAPDKVDESKVHIPSLFVSTSSYNLLW 212

Mouse   160 DEFTYEKGGHIILVPELSLPLEYY---------LIPFLIIVG---ICLILIVIFMITKFVQD-RH 211
            .:          |:.....||:.|         ..|||:...   |.||.:....|.||::. |.
pombe   213 SD----------LLHSYRQPLKLYAKPEELGDMFWPFLLCFSPSIIMLITVQALAIRKFIRTYRT 267

Mouse   212 RNRRNRLRKDQLKKLPVHKFKK----GDEYDV-------------------------CAICLEEY 247
            :::..|..:|    ||.....:    .:|.::                         |.||||.:
pombe   268 KSKTRRFIED----LPSRTISREGFYSEEEEIENSTQNGELVPLMDESTRRATFGVECVICLESF 328

Mouse   248 EDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVP 287
            ..|||:..|||.|.:|..|:..|:...:..||.|..:|.|
pombe   329 TKGDKVVALPCKHEFHRPCIAKWIVDYRHACPTCNTEVPP 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf13	NP_001106884.1	PA_C_RZF_like	23..180	CDD:239038	39/149 (26%)
		RING-H2_RNF167	238..283	CDD:319711	18/69 (26%)
		RING-H2 finger (C3H2C3-type)	240..281	CDD:319711	17/40 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..381		1/2 (50%)
SPAC57A7.09	NP_593372.1	COG5540	1..369	CDD:227827	76/299 (25%)
		Peptidases_S8_S53	<144..211	CDD:299169	25/67 (37%)
		zf-RING_2	320..362	CDD:290367	17/41 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2091
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm59825
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1776
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790