DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prkra and stau

DIOPT Version :9

Sequence 1:	XP_030106794.1	Gene:	Prkra / 23992	MGIID:	1344375	Length:	365	Species:	Mus musculus
Sequence 2:	NP_476751.1	Gene:	stau / 37065	FlyBaseID:	FBgn0003520	Length:	1026	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	90/383 - (23%)
Similarity:	133/383 - (34%)	Gaps:	109/383 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse     2 AERGG---------------AERLGREGVWPALPRRGPASPSFSSCPLAGGRQAAIRGASKRQRG 51
            :|.||               |.:||:...:...|.:.|.:.|......|||......|....|..
  Fly   388 SEEGGPMRTHITPTVELNALAMKLGQRTFYLLDPTQIPPTDSIVPPEFAGGHLLTAPGPGMPQPP 452

Mouse    52 HAP-------LGNWPTWRGRTQIHTSLDCCGQPSLLAMSHSRHRAEAPPLQREDSGTFSLGKMIT 109
            ..|       |||     |...|         ||.....|..|.....|...:....|:|...:.
  Fly   453 PPPAYALRQRLGN-----GFVPI---------PSQPMHPHFFHGPGQRPFPPKFPSRFALPPPLG 503

Mouse   110 AKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVT--VGDITCTGEGTSKKLAKHRA 172
            |.....|            |.|.         ..|||...::|  ||.....|.|.:.:.|||.|
  Fly   504 AHVHHGP------------NGPF---------PSVPTPPSKITLFVGKQKFVGIGRTLQQAKHDA 547

Mouse   173 AEAAINILKANASICF--AVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPA 235
            |..|:.:||..|....  |:.|.:.....|.|.:|::.||..:.:.:|       :.:.:|.|||
  Fly   548 AARALQVLKTQAISASEEALEDSMDEGDKKSPISQVHEIGIKRNMTVH-------FKVLREEGPA 605

Mouse   236 HKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLR 300
            |.:.:.|.|.:.|.:..|:|..||.:|:.||||.|.:...:.|     ||            ..:
  Fly   606 HMKNFITACIVGSIVTEGEGNGKKVSKKRAAEKMLVELQKLPP-----LT------------PTK 653

Mouse   301 NSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIGQLWMGGQASIGPTRT 358
            .:|      |||..:..|..      |..|:.:|..::..|            |||:|
  Fly   654 QTP------LKRIKVKTPGK------SGAAAREGSVVSGTD------------GPTQT 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prkra	XP_030106794.1	DSRM_PRKRA_rpt1	113..183	CDD:380718	19/71 (27%)
		DSRM_PRKRA_rpt2	207..273	CDD:380720	21/65 (32%)
		DSRM_SF	320..>350	CDD:381777	4/29 (14%)
stau	NP_476751.1	DSRM	312..375	CDD:214634
		DSRM	<529..555	CDD:294045	9/25 (36%)
		DSRM	579..644	CDD:214634	23/71 (32%)
		DSRM	712..780	CDD:214634
		Staufen_C	<953..1020	CDD:293091
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810