Protein Alignment Pacsin1 and Cip4

DIOPT Version :9

• Sequence 1: NP_001273672.1
• Gene: Pacsin1 / 23969
• MGIID: 1345181
• Length: 441
• Species: Mus musculus
• Sequence 2: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Alignment Length: 576
• Identity: 104/576 - (18%)
• Similarity: 193/576 - (33%)
• Gaps: 184/576 - (31%)

Mouse    10 EEITDSFWEVGNYKRTVKRIDD--GHR---------------------LCNDLMSCVQERAKIEK 51
            ||..:.|..|..::..:|.:.|  |.|                     |..:...|:.:.|.:::
  Fly   123 EEEDNEFTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQ 187

Mouse    52 AYAQQLT--DWAKR-----WRQLIEKGPQYGSLERAWGAMMTEADK-----VSELHQ--EVKNSL 102
            ....||:  |.|||     :|...:....|...:........|.::     .|::.|  :.||..
  Fly   188 NLTTQLSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEY 252

Mouse   103 LNEDLEKVKNWQKDAYHKQIMG--------------GFKE------------------------- 128
            .|: |:|..|.|:..|...:..              ||:|
  Fly   253 ANQ-LQKTNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVK 316

Mouse   129 ----TKEAEDGFRKAQK-----------PWAKKMK-ELEAAKKAYHLACKEERLAMTREMNS--- 174
                ..|.||.|:..::           |:....| :.::.:.:::.......|.:...|::
  Fly   317 AGESINEKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTSNHLTIRGTMSANKL 381

Mouse   175 -----------KTEQSVTPEQQ-------------KKLVDKVDKCRQDV-QKTQEK----YEKVL 210
                       ..:.|:|.:.|             |||..|:.:..|:: |:|:.:    ..|::
  Fly   382 KKRVGIFNIFGSNKNSLTADGQKEDFSDLPPNQRRKKLQAKIAELTQNIAQETKARDGLMKMKIV 446

Mouse   211 EDVGKT--TPQYMEGMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYMHVYRELEQAIR 273
            .:...:  .|..:||      |..:.|.|    |:::.:|:|::....|.:|.:.......||.|
  Fly   447 YEANSSLGNPMTVEG------QLNESEHK----LEKLKVDLKKYQGFLEKASQVPTATSSPQASR 501

Mouse   274 GADAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTAKKEKQPKKAEGATL-------SNATGA 331
            . ..|...|..|.::|..     ....:...|.|.......:...:...|.:       :|.:.:
  Fly   502 N-QLQNGHRTSRHSNGSA-----DDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSAS 560

Mouse   332 VES------TSQAGD-RGSVSSYDRGQT--YATEWSDDESGNPFGGNEANGGANPFEDDAKGVRV 387
            .||      ||..|. :||.:....|:.  |.||   .|:.||.|                  :.
  Fly   561 PESGLGTSHTSLPGSGQGSANENAIGEDTYYETE---VETLNPVG------------------KC 604

Mouse   388 RALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSG----QLGLYPANYVE 439
            ||||.::...:..:....|:||..:..:...||.|.|.::.    ..|..|.:|:|
  Fly   605 RALYPFEASSEGSIPMSEGEELQVIEIDQGDGWTRVRRENNSNGWDEGFVPTSYIE 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pacsin1	NP_001273672.1	F-BAR_PACSIN1	16..273	CDD:153364	63/382 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..380		19/98 (19%)
		SH3_PACSIN1-2	385..440	CDD:212931	15/59 (25%)
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	33/196 (17%)
		HR1_CIP4-like	412..488	CDD:212009	18/85 (21%)
		SH3_CIP4-like	603..661	CDD:212844	15/58 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940