Protein Alignment FXN and YFH1

DIOPT Version :9

• Sequence 1: NP_000135.2
• Gene: FXN / 2395
• HGNCID: 3951
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_010163.1
• Gene: YFH1 / 851437
• SGDID: S000002278
• Length: 174
• Species: Saccharomyces cerevisiae
• Alignment Length: 101
• Identity: 43/101 - (42%)
• Similarity: 62/101 - (61%)
• Gaps: 4/101 - (3%)

Human    95 YERLAEETLDSLAEFFEDLAD-KPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSS 158
            |...|::.||.|.:..|:|:: .|....|.::|  .||:|:::.. .||||||||.|||||||:|
Yeast    73 YHEEADDYLDHLLDSLEELSEAHPDCIPDVELS--HGVMTLEIPA-FGTYVINKQPPNKQIWLAS 134

Human   159 PSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKAL 194
            |.|||.|:|.....||...:|..|.::|..|:.||:
Yeast   135 PLSGPNRFDLLNGEWVSLRNGTKLTDILTEEVEKAI 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FXN	NP_000135.2	mito_frataxin	94..192	CDD:132463	41/97 (42%)
YFH1	NP_010163.1	mito_frataxin	72..168	CDD:132463	41/97 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159048330
Domainoid	1	1.000	79	1.000	Domainoid score	I2269
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1580
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004275
OrthoInspector	1	1.000	-	-		oto145540
orthoMCL	1	0.900	-	-		OOG6_102217
Panther	1	1.100	-	-	LDO	PTHR16821
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3009
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.790