| Sequence 1: | NP_001277963.1 | Gene: | Mapk7 / 23939 | MGIID: | 1346347 | Length: | 806 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_477361.1 | Gene: | p38b / 34780 | FlyBaseID: | FBgn0024846 | Length: | 365 | Species: | Drosophila melanogaster |
| Alignment Length: | 345 | Identity: | 162/345 - (46%) |
|---|---|---|---|
| Similarity: | 229/345 - (66%) | Gaps: | 16/345 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Mouse 114 IIAIKDILKPTVP---YGEFRSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHS 175
Mouse 176 AQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
Mouse 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLP--P 303
Mouse 304 RQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFD 368
Mouse 369 REALTRERIKEAIVAEIEDF 388 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mapk7 | NP_001277963.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..23 | ||
| Required for cytoplasmic targeting | 2..77 | 9/27 (33%) | |||
| STKc_ERK5 | 49..384 | CDD:270842 | 160/339 (47%) | ||
| Required for binding to MAP2K5 | 78..139 | 26/63 (41%) | |||
| Necessary for oligomerization | 140..406 | 125/251 (50%) | |||
| TXY | 219..221 | 1/1 (100%) | |||
| May not be required for kinase activity, required to stimulate MEF2C activity | 407..806 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 424..473 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 488..727 | ||||
| Nuclear localization signal | 505..539 | ||||
| p38b | NP_477361.1 | STKc_p38 | 8..353 | CDD:143356 | 162/345 (47%) |
| S_TKc | 24..311 | CDD:214567 | 147/296 (50%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0660 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||