back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ggt5 and CG4829

DIOPT Version :9

Sequence 1:	NP_035950.2	Gene:	Ggt5 / 23887	MGIID:	1346063	Length:	573	Species:	Mus musculus
Sequence 2:	NP_728030.2	Gene:	CG4829 / 32672	FlyBaseID:	FBgn0030796	Length:	822	Species:	Drosophila melanogaster

Alignment Length:	568	Identity:	184/568 - (32%)
Similarity:	289/568 - (50%)	Gaps:	63/568 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse    39 GAFTRAAVAADSKICSDIGRAILQQRGSPVDAAIAALVCTGVVNPQSMGLGGGVVFTIYNASTGK 103
            |.:...||::|:..||.||..|||:.||.||||||||:|.|::..||||:|||.:..:||.....
  Fly   285 GVYQHGAVSSDNLECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNRKERH 349

Mouse   104 VEIINARETVPASYDQGLL-----NQCKNVLPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLF 163
            ...|:|||..|....:.:.     |..|.  ||.     |.||||:.||..||::.|:||||:|.
  Fly   350 ATAIDAREVAPYEATEDMFAQQPENSDKG--PLS-----IAVPGEVMGYHVAHQKFGQLPWAELV 407

Mouse   164 QPTIALLREGFRV------------PFILSQ-----FLNNSILRPHLSASTLRQLFFNGTETLRS 211
            .|::.|..:|:.|            |:|...     :||....:||::.:.::
  Fly   408 APSLELCEKGYHVSQHMERALDIALPYIKEHEQYQIYLNAETGKPHVAGTVVK------------ 460

Mouse   212 QDPFPWPALANTLETVAKEGAEVLYTGRLGRMLVEDIAKQGSLLTVQDLAAFQPEVVEPLEMPLG 276
                |...|..|.:.:|:.|...:|.|.:.::|.||:...||::...||.:::.:|:..:.|.||
  Fly   461 ----PPKNLCKTYKLLAENGPMDMYNGTIAKLLAEDLQDMGSIILADDLESYEADVINSITMDLG 521

Mouse   277 NYTLYSPPPPAGGAILSFILNVLKGFNFSAETVARPGGEVNMYHHLVETLKFAVGQRWRLWDPSS 341
            :.|||..||.:.|::::.:|.:|:|:||:|:.::....:....|...|.:|||..||..|.|...
  Fly   522 DDTLYVVPPVSSGSVVAHVLAILQGYNFTAQDLSTEELKARTIHRFAEAMKFAFAQRPELGDMHF 586

Mouse   342 HPGIQNISRDLLREDLAQRIRQQIDGRGDHHQLSHYNLTGVRGNRM----GTSHVSVLGEDGSAV 402
            ....:.:|| |...|...:.|.:|:   |.|.|......|.....:    |||::.||..:|.||
  Fly   587 IDARELVSR-LNSPDFGDQNRAKIN---DSHVLPDAQAYGANFAAIEDLDGTSNLVVLAPNGDAV 647

Mouse   403 AATSTINTPFGAMVYSPRTGILLNNELLDLCWRH----MPTSPITPPPVPGERPPSSMVPSILVN 463
            :.||:||:.||:.:..|||||:|||.:.|...::    :|.|....... .:|..||..|.:|.:
  Fly   648 SVTSSINSYFGSGLIGPRTGIVLNNGMNDFAVKNNIFALPQSQSNKIEA-HKRAMSSQSPILLAD 711

Mouse   464 KGQGSKLVIGGAGGELIISAVAQTIMNKLWLGFDLTEAIASP-ILHVNSKGHVEYEPK-FNQEVQ 526
            |....|:|||.|||..||.||.:...|.||.|.||.:|:.:| ..|......:|||.. |.:.:.
  Fly   712 KDGNMKMVIGAAGGSKIIPAVVEVAANVLWFGKDLRQAVDAPRFYHQLMPDVLEYEEDGFTESLL 776

Mouse   527 KGLQDRG-QIQSQSQRPVFLNAVQAVFQEGPCVYAASDLRKAGKASGY 573
            :.|..|| :::|.|.:..  :.|.|:.:....:||.:|.||.|..:|:
  Fly   777 QLLTKRGHKLKSISVKTG--SVVTAISRNATAIYANADYRKRGGVAGF 822

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.