Protein Alignment Gdf15 and scw

DIOPT Version :9

• Sequence 1: NP_001317616.1
• Gene: Gdf15 / 23886
• MGIID: 1346047
• Length: 303
• Species: Mus musculus
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 228
• Identity: 57/228 - (25%)
• Similarity: 86/228 - (37%)
• Gaps: 37/228 - (16%)

Mouse   101 QLLLRVNRASLSQGLPEAYRVHRALLLLTPTARPWDITRPLKRALSLR-------------GPRA 152
            ::|..||..|..:|..|        ..||.|.|.|...:.|:|...||             |...
  Fly   183 RILGSVNTTSSQRGWLE--------FNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVT 239

Mouse   153 P-ALRLRLTP--------PPDLAMLPSGGTQLELRLRVAAGRGRRSAHAHPRDSCPLGPGRCCHL 208
            | |.|..|.|        |..|..:.....:.:|..|.|.|.........|.|.  ..|.:.|..
  Fly   240 PQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDL--YRPPQSCER 302

Mouse   209 ETVQATLEDLGWSDWVLSPRQLQLSMCVGECPH---LYRSANTHAQIKARLHGLQPDKVPAPCCV 270
            .......::|...:||::|::.:...|.|.|..   ...:|..||.::..:|..|| .:|.||||
  Fly   303 LNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQP-HLPKPCCV 366

Mouse   271 PSSYTPV-VLMHRTDSGVSLQTYDDLVARGCHC 302
            |:....: :|.:..:..:.|..|...||:.|.|
  Fly   367 PTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdf15	NP_001317616.1	None
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	21/78 (27%)
		TGFB	300..400	CDD:214556	27/101 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810