Protein Alignment Ets2 and pnt

DIOPT Version :9

• Sequence 1: NP_035939.3
• Gene: Ets2 / 23872
• MGIID: 95456
• Length: 468
• Species: Mus musculus
• Sequence 2: NP_524461.2
• Gene: pnt / 42757
• FlyBaseID: FBgn0003118
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 626
• Identity: 204/626 - (32%)
• Similarity: 266/626 - (42%)
• Gaps: 206/626 - (32%)

Mouse    23 LKRQPAFDTFDGSLFAVLPSLSEDQTLQEVPTGLDSVSHDSASCELPLLTPCSKAVMSQALKATF 87
            :|.:|.....|   ...|..:|:.:...||||.            ||.|||.:...:::.|||:|
  Fly   117 IKEEPIHGCKD---LCSLSDISDHEASLEVPTA------------LPPLTPGTNRKVNEVLKASF 166

Mouse    88 SGFQKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLHQF-GMNGQMLCNLGKERFLELA 151
            :.::||.::..|.|:|..|:|:.|..||.||.||||||::||..| .|.|:.:.:||||:||.:.
  Fly   167 ASWEKEVQKCNITKDPREWTEEHVIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAIT 231

Mouse   152 PDFVGDILWEHLEQMIKENQEKTED-----------------------QYEENSHLNAVPHWINS 193
            |.|.||||||||:.:.|:.::..||                       .|...:|.|:....|||
  Fly   232 PPFTGDILWEHLDILQKDCEKPNEDIVHGNSFESATTASVCGSDHQVANYPNETHANSNNSSINS 296

Mouse   194 NTLGFSMEQAPYGMQAPNYPKDNL-------------------LDSMCPP----SATPAALGS-- 233
            .   .||:   |...|.|....|.                   :::..||    |..|...||
  Fly   297 R---LSMD---YVTSAGNSDNKNFHRATPHSHNGYNTSNTHDRINNSTPPQQQQSQQPTVNGSGS 355

Mouse   234 -----ELQMLPKS--RLNTVNVNYCSISQDFPSSNVNLLNNNSG--------------------- 270
                 ...|||.:  :.|..|.|..|.:.:..|:|    |||||
  Fly   356 ASSNNNNSMLPPAVQQSNNENNNTSSSNTNNSSNN----NNNSGGSNNSNAGSNNNNNNNNNINF 416

Mouse   271 ----------------------------------------------------------------- 270
                                                                             
  Fly   417 MAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSG 481

Mouse   271 ------------KPKDHDSPENGGDS----------------FESSDSLLRSWNSQSSLLDVQRV 307
                        ..:||.|.::.|.:                .:||.....|:..::...| ...
  Fly   482 GGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHD-GYP 545

Mouse   308 PSFESFEEDCSQSLCLSKLTMSFKDYIQERSDPVEQGKPV-IPAAVLAG---------FTGSGPI 362
            |.|..::....||:......|...........|......: :...:|.|         |||||||
  Fly   546 PEFTPYDAQSFQSMGPQPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPI 610

Mouse   363 QLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKN 427
            ||||||||||.||:||||||||||||||||.||||||||||.|||||||||||||||||||||||
  Fly   611 QLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKN 675

Mouse   428 IIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED 468
            |||||:|||||||||||||||:|.|||||.|...::.:.:|
  Fly   676 IIHKTAGKRYVYRFVCDLQNLVGHTPEELVAKYDLKIEKKD 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ets2	NP_035939.3	SAM_PNT-ETS-2	85..173	CDD:188884	42/88 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..290		11/141 (8%)
		ETS	361..445	CDD:197710	78/83 (94%)
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879	37/70 (53%)
		ETS	609..693	CDD:197710	78/83 (94%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I3823
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2460
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	1	1.000	-	-		FOG0003547
OrthoInspector	1	1.000	-	-		otm42562
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11849
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10367
SonicParanoid	1	1.000	-	-		X2422
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.960