DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets2 and Ets65A

DIOPT Version :9

Sequence 1:	NP_035939.3	Gene:	Ets2 / 23872	MGIID:	95456	Length:	468	Species:	Mus musculus
Sequence 2:	NP_001303373.1	Gene:	Ets65A / 38700	FlyBaseID:	FBgn0005658	Length:	728	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	108/323 - (33%)
Similarity:	147/323 - (45%)	Gaps:	82/323 - (25%)

- Green bases have known domain annotations that are detailed below.

Mouse   191 INSNTLGFSMEQAPYGMQAPNYPKDNLLDSMCPP----------------------------SAT 227
            ::|:|.|. :..:..|:|.      :.||::.||                            ||.
  Fly   126 VSSSTAGV-LSSSGNGVQR------HRLDTLQPPSGCSPAVTQHGVITSSAGQVTSGTLDAVSAA 183

Mouse   228 P------AALGSELQMLPKSRLNTVNVNYCSISQDFPSSNVNLLNNNSGK---PKDHDSPENGGD 283
            |      |:..|.::...::..:|::....|.....|||:.:..::..|:   .|..::...||.
  Fly   184 PALPSLTASSSSHVEHKVRADKSTLDCATTSSHAAAPSSSSSASDHQQGRISGSKSSNTSGTGGG 248

Mouse   284 SFESS-------DSLLRSWNSQSSLLDVQRVPSFESFEEDCSQSLCLSKLTMSFKDYIQERS-DP 340
            :..|.       .|...||.|.||..               ||....:.|.:....:.|.|. ||
  Fly   249 ASASGGGGSALYSSYKSSWGSHSSTQ---------------SQGYSSNALGIKHDPHSQLRQPDP 298

Mouse   341 VEQGKPVIPAAVLAGFTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKR 405
            .:...|.  ::.||. :|||.|||||||||||||.:..|.|:|.|...||||.||||||||||:|
  Fly   299 YQMFGPT--SSRLAS-SGSGQIQLWQFLLELLSDSNNASCITWEGTNGEFKLTDPDEVARRWGER 360

Mouse   406 KNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED 468
            |:||.|||:||||.|||||||||:.|..||||.|:|  |.|.|...|          ||...|
  Fly   361 KSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF--DFQGLAAAT----------QPAASD 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets2	NP_035939.3	SAM_PNT-ETS-2	85..173	CDD:188884
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..290		5/37 (14%)
		ETS	361..445	CDD:197710	58/83 (70%)
Ets65A	NP_001303373.1	ETS	316..401	CDD:197710	60/86 (70%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810