Protein Alignment Def8 and Plekhm1

DIOPT Version :9

• Sequence 1: XP_036009874.1
• Gene: Def8 / 23854
• MGIID: 1346331
• Length: 499
• Species: Mus musculus
• Sequence 2: NP_611639.1
• Gene: Plekhm1 / 37520
• FlyBaseID: FBgn0034694
• Length: 720
• Species: Drosophila melanogaster
• Alignment Length: 474
• Identity: 126/474 - (26%)
• Similarity: 200/474 - (42%)
• Gaps: 103/474 - (21%)

Mouse    77 HHEQEPSEKV-TSEDTLPELPAGEP--EFHYSERMMDLGLSEDHFSRPVGLFLASDVQQLRQAIE 138
            :.||...:|. |:|....|.|:|..  ....|.|.||.....|
  Fly   280 NEEQTGGDKAETNETAEQEAPSGSKTRSRKKSNRQMDSSSFAD---------------------- 322

Mouse   139 ECKQVILELPEQSEKQKDAVVRLIHLRLKLQELK----DPNEEEPNIRVLLEHRFYKEKSKSVKQ 199
                :.||.|....:..:::..|:..... .:|:    .|.||      |...||: ::|.||..
  Fly   323 ----LDLEAPSLLPQGSNSLSNLMQTSWS-GDLEATPTSPTEE------LTGSRFF-QRSVSVSS 375

Mouse   200 -------TCDKC--NTII------------WGLIQTWYTCTGCCYRCHSKCLNLI-----SKPCV 238
                   |.|:|  |.::            |.  :.|..     :|..:..||:.     :.|.:
  Fly   376 SVSLRSPTTDRCSYNALLRKHESNRESGAGWS--EIWEK-----FRASASNLNVAQPQRDTDPPI 433

Mouse   239 SSKVSH------QAEYEL---------------NICP---ETGLDSQDYRCAECRAPISLRGVPS 279
            |..:|.      .:|:||               .:|.   |.|||:|.:.|..|:.|:.: |. |
  Fly   434 SEDLSDLQSLDTNSEFELLTSEFDMVELQQMVAQLCQLAREPGLDAQGFLCKSCQHPLGI-GY-S 496

Mouse   280 EARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLL 344
            ..:.|.::|.|||:.|...::.:||||:::||||....||:.:..:||...|.|.|.::.:||.:
  Fly   497 NFQVCAFSGSYYCNSCMDVEMQLIPARIIYNWDFRKYSVSKRAATFLAEFRSHPFLDMQLLNPRI 561

Mouse   345 FNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQDRQHFVENDEMYSIQDLLEVHMGRL 409
            :...:.:.|::.||..:..::.|..||..:....|..|...|::..|:..:|||.||..:..|.|
  Fly   562 YFASDAMAELQSLRIRLNFIRAYLYTCAPSSIELLQNQFAGREYLYEHIHLYSIADLALIQRGVL 626

Mouse   410 SCSLTEIHTLFAKHIKLDCERCQAKGFVCELCKEGDVLFPFD-SHTSVCNDCSAVFHRDCYYDNS 473
            ...|.:...|...|: |.|..|..|||:||:|:...||:||. |.|..|..|.||||.:| .:..
  Fly   627 CQQLQKAFKLGEAHV-LKCRLCHLKGFICEICQSPRVLYPFHISTTFRCLACGAVFHAEC-LNEK 689

Mouse   474 TTCPKCARLTLRKQSLFQE 492
            ..||||.|:..|:....||
  Fly   690 QPCPKCERIRKREDQGLQE 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Def8	XP_036009874.1	C1_DEF8	182..242	CDD:410369	17/85 (20%)
		zf-RING_9	284..481	CDD:404739	69/197 (35%)
Plekhm1	NP_611639.1	RUN	54..185	CDD:280855
		zf-RING_9	500..700	CDD:290612	70/201 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1829
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4753
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177737at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770