Protein Alignment Kcns3 and Shawl

DIOPT Version :9

• Sequence 1: NP_001162036.1
• Gene: Kcns3 / 238076
• MGIID: 1098804
• Length: 491
• Species: Mus musculus
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 139/525 - (26%)
• Similarity: 224/525 - (42%)
• Gaps: 151/525 - (28%)

Mouse    14 EELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPFLFRY 78
            |..:.|||.|.:....::||.:.|.|||.:|         .|...:|.....||:|||:|.:|..
  Fly     4 ENRIILNVSGIRYETYKATLKKIPATRLSRL---------TEALANYDPVLNEYFFDRHPGVFTQ 59

Mouse    79 VLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSSRYQERKEESH-----DKDWDQKSN 138
            :||:|.|||||...::|...|.:|:|:||::...::.||.|.|...::..:     ||      .
  Fly    60 ILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDK------L 118

Mouse   139 DVSTDSSFEESSL----FEKELEKFDELRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASI 199
            |:..:...||...    ||:.|...:...:.:::.|||...:.|:....||::|..|:..:..|:
  Fly   119 DIENEKPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSV 183

Mouse   200 VAMCV------------------------------------------------------------ 204
            ::.|:
  Fly   184 ISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVT 248

Mouse   205 ----HSMSEF---------------------QNEDGEVDDPVLEG-------------------- 224
                :|...|                     :|.:|.:.:..:|.
  Fly   249 NYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQP 313

Mouse   225 ------VEIACIAWFTGELAIRLVAAPSQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIE 283
                  ||:.|..||..|:.|||:.:|:..:|.|:|:|||||.:.:.||           ::.::
  Fly   314 HEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-----------TDVMQ 367

Mouse   284 NMGKVVQILR---LMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSV 345
            .||:...:|.   ::||.|:.||.|||.|||.|..|.:.|..|:.||:.||.:||..|:.|.|..
  Fly   368 RMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYA 432

Mouse   346 EK--DEHKSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKIIASTCIICGILVVALPITIIFNK 408
            ||  |...:...|||:..|||.::||||||||..|.|..|..:.:.|.:.|:|.:|||:.:|.:.
  Fly   433 EKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSN 497

Mouse   409 FSKYY 413
            ||.:|
  Fly   498 FSMFY 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcns3	NP_001162036.1	BTB_POZ_KCNS3	15..122	CDD:349735	37/106 (35%)
		Ion_trans	184..417	CDD:366146	88/346 (25%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	370..375		4/4 (100%)
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	35/100 (35%)
		BTB_2	7..97	CDD:280393	34/98 (35%)
		Ion_trans	307..506	CDD:278921	77/207 (37%)
		Ion_trans_2	<449..499	CDD:285168	21/49 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910