Sequence 1: | NP_004295.2 | Gene: | ALK / 238 | HGNCID: | 427 | Length: | 1620 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_524080.1 | Gene: | Tak1 / 39659 | FlyBaseID: | FBgn0026323 | Length: | 678 | Species: | Drosophila melanogaster |
Alignment Length: | 464 | Identity: | 119/464 - (25%) |
---|---|---|---|
Similarity: | 192/464 - (41%) | Gaps: | 91/464 - (19%) |
- Green bases have known domain annotations that are detailed below.
Human 1102 TSSISDLKE--VPRKNITLIRGLGHGAFG----EVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQD 1160
Human 1161 ELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLR-ETRPRPSQPSSLAML 1224
Human 1225 DLLHVARDIACGCQYLE---ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKG 1286
Human 1287 GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEF-VTSGGRMDP 1350
Human 1351 P--KNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPV 1413
Human 1414 RPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGK-----AAKKPTAAEISVRVPRGPAVEG 1473
Human 1474 GHVNMAFSQSNPPSELHKVHGSR--NKP-----TSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRG 1531
Human 1532 NLGLEGSCT 1540 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ALK | NP_004295.2 | MAM | 266..427 | CDD:279023 | |
MAM | 266..424 | CDD:99706 | |||
LDLa | 441..467 | CDD:197566 | |||
MAM | 480..636 | CDD:279023 | |||
MAM | 480..631 | CDD:99706 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 650..674 | ||||
FXa_inhibition | 987..1021 | CDD:291342 | |||
PTKc_ALK_LTK | 1109..1385 | CDD:270632 | 85/288 (30%) | ||
Pkinase_Tyr | 1116..1383 | CDD:285015 | 84/277 (30%) | ||
Inhibitor binding | 1197..1199 | 1/1 (100%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1408..1463 | 12/59 (20%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1514..1540 | 5/25 (20%) | |||
Tak1 | NP_524080.1 | TyrKc | 19..264 | CDD:197581 | 83/274 (30%) |
STKc_TAK1 | 25..275 | CDD:270960 | 82/279 (29%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |