Protein Alignment MTCH1 and Mtch

DIOPT Version :9

• Sequence 1: XP_005249035.1
• Gene: MTCH1 / 23787
• HGNCID: 17586
• Length: 427
• Species: Homo sapiens
• Sequence 2: NP_001246525.1
• Gene: Mtch / 38026
• FlyBaseID: FBgn0027786
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 105/307 - (34%)
• Similarity: 165/307 - (53%)
• Gaps: 42/307 - (13%)

Human    88 LGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGL 152
            |..||:|..||..|.|.|||:|:||:.|..|.::||:.::.||:.|.||.:|.::||..|.:|||
  Fly    23 LRLGVSAALHPFEYSKTLIQLGYEPIAPLPGKSILGKPIMKLPNIFQYAGHIRRIDGFYGCYRGL 87

Human   153 SPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTS-------LKKVVKETSYEMMMQCVSRM 210
            :|:|:.:.::.|....:......::.|:  ||||.:.|       .||.:|.   ::::.....:
  Fly    88 APKLVGSLVAMVVSDRVADQLGLEQPEE--NKDDSQLSDEELYVQFKKSLKR---DIVLMVSGVV 147

Human   211 LAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAH 275
            .:||.||||:|.|.||||||..|:.::.|:.:|:|.||:.|||.||:|.||||:..|...:...:
  Fly   148 ASHPFHVISLRMMAQFVGRETLYTSIVGSVAEIWKSEGIAGFFAGLVPKLLGDLACLVLSSSTIY 212

Human   276 FINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNC 340
            .:|.|::.|.       ||...|.|           :|:|    |||.|.||..:|....||:..
  Fly   213 ILNKYIIKDK-------LGRQYNSG-----------FTQF----AVSSLLYPLQVVSTCSAVSGS 255

Human   341 GLQAGLPPYSPVFKSWIHCWKYLSVQ------VSKHWTAEAF--PVL 379
            .|.|..||..|.:::|:.||..|.|:      .|..|.:::.  ||:
  Fly   256 RLMAAQPPIMPAYRNWVDCWNDLQVRGELKRGSSLFWRSQSISSPVI 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTCH1	XP_005249035.1	Mito_carr	76..173	CDD:278578	33/84 (39%)
		Mito_carr	206..>264	CDD:278578	29/57 (51%)
Mtch	NP_001246525.1	Mito_carr	142..222	CDD:278578	33/79 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155481
Domainoid	1	1.000	77	1.000	Domainoid score	I8890
eggNOG	1	0.900	-	-		E1_KOG2745
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3771
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49093
OrthoDB	1	1.010	-	-		D1439019at2759
OrthoFinder	1	1.000	-	-		FOG0004199
OrthoInspector	1	1.000	-	-		mtm8643
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10780
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4015
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.870