DRSC/TRiP Functional Genomics Resources

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Protein Alignment POTEH and acta1a

DIOPT Version :9

Sequence 1:NP_001129685.1 Gene:POTEH / 23784 HGNCID:133 Length:545 Species:Homo sapiens
Sequence 2:NP_001017750.1 Gene:acta1a / 550445 ZFINID:ZDB-GENE-050417-267 Length:377 Species:Danio rerio


Alignment Length:282 Identity:56/282 - (19%)
Similarity:105/282 - (37%) Gaps:87/282 - (30%)


- Green bases have known domain annotations that are detailed below.


Human   108 CCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKNK---VGPWGDYD----DSA- 164
            |..|||....|.:||....|:              ||...|..:::   || .|..|    |.| 
Zfish    12 CDNGSGLVKAGFAGDDAPRAV--------------FPSIVGRPRHQGVMVG-MGQKDSYVGDEAQ 61

Human   165 ----FMEPRYHVRR------EDLDKLHRAAWWG--KVPRKDLIVMLKDTDMN-KKDKQKRTALHL 216
                .:..:|.:..      :|::|:....::.  :|..::...:|.:..:| |.:::|.|.:..
Zfish    62 SKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMF 126

Human   217 ASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLE--HGTDPNIPDEYGNTA 279
            .:.|    |..:.:..:..|::..:.:.|.:              :|:  .|...|:| .|...|
Zfish   127 ETFN----VPAMYVAIQAVLSLYASGRTTGI--------------VLDSGDGVTHNVP-IYEGYA 172

Human   280 LHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQK---------QQVVKFLIKKKANL 335
            |.:||...|        |.|.|        ||..|:.:..::         :::|:. ||:|...
Zfish   173 LPHAIMRLD--------LAGRD--------LTDYLMKILTERGYSFVTTAEREIVRD-IKEKLCY 220

Human   336 NALDRYGRTALILAVCCGSASI 357
            .|||....    :|....|:|:
Zfish   221 VALDFENE----MATAASSSSL 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POTEHNP_001129685.1 Ank_4 180..230 CDD:290365 8/52 (15%)
ANK 1 180..208 4/30 (13%)
ANK 204..329 CDD:238125 25/136 (18%)
ANK 2 209..238 5/28 (18%)
ANK repeat 211..240 CDD:293786 4/28 (14%)
Ank_2 214..306 CDD:289560 17/93 (18%)
ANK repeat 242..273 CDD:293786 4/32 (13%)
ANK 3 242..271 3/30 (10%)
ANK 270..394 CDD:238125 24/97 (25%)
ANK repeat 275..306 CDD:293786 9/30 (30%)
ANK 4 275..304 9/28 (32%)
Ank_2 280..372 CDD:289560 20/87 (23%)
ANK repeat 308..339 CDD:293786 8/39 (21%)
ANK 5 308..337 7/37 (19%)
ANK repeat 341..372 CDD:293786 3/17 (18%)
ANK 6 341..370 3/17 (18%)
ANK 7 374..404
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 406..524
acta1aNP_001017750.1 NBD_sugar-kinase_HSP70_actin 4..377 CDD:302596 56/282 (20%)
ACTIN 7..377 CDD:214592 56/282 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100127
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.710

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