Protein Alignment PITPNB and vib

DIOPT Version :10

• Sequence 1: XP_011528354.1
• Gene: PITPNB / 23760
• HGNCID: 9002
• Length: 274
• Species: Homo sapiens
• Sequence 2: NP_001262726.1
• Gene: vib / 42306
• FlyBaseID: FBgn0267975
• Length: 273
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 167/277 - (60%)
• Similarity: 209/277 - (75%)
• Gaps: 15/277 - (5%)

Human     6 MEKCRVVLPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYEK----DGE--KGQYTHKIY 64
            :::.||.||.:|:||||.||:|||||||..||||||||||||||:|.    .|:  .||||:|||
  Fly     3 IKEFRVTLPLTVEEYQVAQLFSVAEASKENTGGGEGIEVLKNEPFEDFPLLGGKYNSGQYTYKIY 67

Human    65 HLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNE-YMKDDFFIKIETWH-KPDLGTLENV 127
            ||:|||||::|::||:|||..||:|||||||||||:||. ||..:|.|.|.:.| :.||||::||
  Fly    68 HLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTVDNV 132

Human   128 HGLDPNTWKTVEIVHIDIADRSQVEPADYKADEDPALFQSVKTKRGPL-GPNWKKELANSPDCPQ 191
            |.|.|:..|..||||||||: ..|.|||||.||||..:||.||.|||| |.:|||.:.     |.
  Fly   133 HELTPDKLKVREIVHIDIAN-DPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKKHVN-----PV 191

Human   192 MCAYKLVTIKFKWWGLQSKVENFIQKQEKRIFTNFHRQLFCWIDKWIDLTMEDIRRMEDETQKEL 256
            |..|||||.:|||:|||::|||||||.|:|:|||||||:||..|:|..|||||||.:||:|::||
  Fly   192 MTCYKLVTCEFKWFGLQTRVENFIQKSERRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKEEL 256

Human   257 ETLRNQGQVRGTSAASD 273
            :..|..|:|||..|.:|
  Fly   257 DKARQVGEVRGMRADAD 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PITPNB	XP_011528354.1	SRPBCC_PITPNA-B_like	10..261	CDD:176897	160/259 (62%)
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	160/263 (61%)