Protein Alignment STX12 and Syx7

DIOPT Version :10

• Sequence 1: NP_803173.1
• Gene: STX12 / 23673
• HGNCID: 11430
• Length: 276
• Species: Homo sapiens
• Sequence 2: NP_730632.1
• Gene: Syx7 / 36173
• FlyBaseID: FBgn0267849
• Length: 282
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 93/279 - (33%)
• Similarity: 161/279 - (57%)
• Gaps: 28/279 - (10%)

Human    13 GPSGPQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQLQHSTNQLAKET 77
            |..|....||..:.|..:.:||::.|..:.::.:::||.|.|||.:|::.|.|:...||||..:|
  Fly    14 GGGGLSEIDFQRLAQIIATSIQKVQQNVSTMQRMVNQLNTPQDSPELKKQLHQIMTYTNQLVTDT 78

Human    78 NELLKELGSLPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIARA------- 135
            |..:.|       :...::|..::|::||:::|:|||..||:|||:.::.||.::.:|
  Fly    79 NNQINE-------VDKCKERHLKIQRDRLVDEFTAALTAFQSVQRKTADIEKTALRQARGDSYNI 136

Human   136 -------RAGSRLSAEERQREEQLVS---FDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQ 190
                   |.||..|:..:|.......   |:......|||:|.:|.|    ||:.::|:|..||:
  Fly   137 ARPPGSSRTGSSNSSASQQDNNSFFEDNFFNRKSNQQQMQTQMEEQA----DLQALEEQEQVIRE 197

Human   191 LEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMCILV 255
            ||.:|:.||:|:|.|..::::||..:||||:.||.:.:.|.:.||.|::|:.|:.|.|||..|||
  Fly   198 LENNIVGVNEIYKKLGALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNKVRKKKLILV 262

Human   256 LVLSVIILILGLIIWLVYK 274
            .:||.::|.:.||:...:|
  Fly   263 GILSAVLLAIILILVFQFK 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STX12	NP_803173.1	Syntaxin_2	30..132	CDD:464199	34/101 (34%)
		SNARE_syntaxin12	181..247	CDD:277229	26/65 (40%)
Syx7	NP_730632.1	Syntaxin_2	30..123	CDD:464199	32/99 (32%)
		COG5325	<97..276	CDD:227635	65/182 (36%)
		SNARE	188..247	CDD:473982	24/58 (41%)