Protein Alignment ARFIP2 and Arfip

DIOPT Version :9

• Sequence 1: NP_001229783.1
• Gene: ARFIP2 / 23647
• HGNCID: 17160
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_650058.1
• Gene: Arfip / 41353
• FlyBaseID: FBgn0037884
• Length: 355
• Species: Drosophila melanogaster
• Alignment Length: 364
• Identity: 169/364 - (46%)
• Similarity: 235/364 - (64%)
• Gaps: 35/364 - (9%)

Human    32 EQDLQQVMVSGPNLNET--SIVSGGYGGSGDGLIPTGKSISCARREVWVGPQRCLVYLREAGVRE 94
            |:.:.:::...|:||::  ::.:|..|||  |::.:..|.|.|......|         ..||..
  Fly     5 ERSIHEMLKDAPSLNDSCGAVHTGTEGGS--GILGSASSHSIAGGGGGGG---------NVGVGV 58

Human    95 LDPLGSG-----RHPSHSTTPSGPGDEVA-RGI--------------AGEKFDIVKKWGINTYKC 139
            ..|.|:.     |:.|..|||..|....: .||              :..|.|.:|.|.|:||||
  Fly    59 GGPFGAPSSLPLRNHSAPTTPMSPSSPPSGNGILSPTDSGSGSIIRTSASKIDSLKNWSISTYKC 123

Human   140 TKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADL 204
            |:|::.|:.|:..||||.|||.|||.||||:|||.|:|:|.||.::|...::.|||||.|:||||
  Fly   124 TRQIMLEKLGKSQRTVDSELEAQIEQLRETQRKYLSILRLTRAFSSHFQHVVVTQHALADSFADL 188

Human   205 SQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYD 269
            :||:||||:||..|:|||:.|.||||.||.|:|||:||:|||..||::|||:|::|||.||:|:|
  Fly   189 AQKNPELQKEFTCNSETQRNLTKNGELLLNALNFFISSVNTLCNKTIDDTLLTIRQYETARIEFD 253

Human   270 AYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLF 334
            |||.|||...  |....:...||..|.::..|:::|||||.|||:|::||:||:||||||||:|.
  Fly   254 AYRMDLENTK--PELTPSAVALEETQRSYAQHKEQYEKLRSDVAVKMQFLDENRIKVMHKQLILL 316

Human   335 HNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEE 373
            |||::|||:||...||.||:||||||:.|.|...||||:
  Fly   317 HNAIAAYFSGNAMALESTLKQFNIKLKSPNAVTGSWLEQ 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARFIP2	NP_001229783.1	BAR_Arfaptin	169..356	CDD:153344	106/186 (57%)
Arfip	NP_650058.1	BAR_Arfaptin	140..338	CDD:153344	116/199 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141623
Domainoid	1	1.000	267	1.000	Domainoid score	I1881
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8234
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2648
Isobase	1	0.950	-	0	Normalized mean entropy	S3987
OMA	1	1.010	-	-		QHG48818
OrthoDB	1	1.010	-	-		D1179170at2759
OrthoFinder	1	1.000	-	-		FOG0003325
OrthoInspector	1	1.000	-	-		otm42052
orthoMCL	1	0.900	-	-		OOG6_105484
Panther	1	1.100	-	-	LDO	PTHR12141
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5434
SonicParanoid	1	1.000	-	-		X2693
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.890