Protein Alignment PLD3 and CG43345

DIOPT Version :10

• Sequence 1: NP_036400.2
• Gene: PLD3 / 23646
• HGNCID: 17158
• Length: 490
• Species: Homo sapiens
• Sequence 2: NP_610096.1
• Gene: CG43345 / 35387
• FlyBaseID: FBgn0263050
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 454
• Identity: 191/454 - (42%)
• Similarity: 262/454 - (57%)
• Gaps: 35/454 - (7%)

Human    35 KARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPAPCYD--PCEAVLVESIPEGLDF-- 95
            |..:::.||||.|:   .::..|..||  ..|.......|.|...  ||:..||||:|.||::
  Fly    51 KHGYIIPVLILFVL---VMIVLLLPWE--TYHRNENGNSPVPVEKPLPCQLELVESLPLGLNYSQ 110

Human    96 ----PNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLRQLQTLAP 156
                |..|    ||..||..||..|.:||||.|.:|||...|.:  :.|...|:::.:||.:...
  Fly   111 WQSHPQLS----STFDAWQLLLGRAKASLDIVSPHWTLRGLDVN--DSSTGPGDQLFQQLLSNGD 169

Human   157 KG---VNVRIAVSKPSGPQPQADLQALLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSAN 218
            .|   :.|||.|::.......||.:.|...||    .|:..:  ..||:|.|:||..|||||:|:
  Fly   170 AGRPKLRVRIVVNRSHDSLWHADARILANYGA----ADVVGI--NFLHSKLWLVDGEHFYLGTAS 228

Human   219 MDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICL 283
            ||||||||.|||||:..||..||.||.|||:|||:||  .:.:|.:||..|.|..||..|:.:.:
  Fly   229 MDWRSLTQRKELGVLARNCPHLALDLGKIFKAYWYLG--SNEVPKSWPWIYHTHINQRRPLLLNI 291

Human   284 NGTPAL-AYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYVAVMNYLPTLEFSHPHRFWPAIDD 347
            |....: |||:::||.|..:|||.:|.|:|..:|.|...||:::|.|.|.|..|:...:||.||:
  Fly   292 NKKHTMRAYLSTSPPELIATGRTRELDAILEAIDKATDVIYLSLMEYSPRLRRSNKLEYWPVIDN 356

Human   348 GLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAALRDNHTHS-DIQVKLFVVPADEAQARIPY 411
            .||||..||||.:::|||.|.:|:||...||.||.|| |..|.. |||::.||||......||..
  Fly   357 ALRRAALERGVAIKVLISWWKYSDPSEDHFLRSLQAL-DKITEGVDIQMRRFVVPTTNELERISG 420

Human   412 ARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLV--TQNGRGGLRSQLEAIFLRDWDSPYS 473
            .|||.|.|:||:|..:||||::||.:||.:||..|::  .:.....||:.|.|||||||.|||:
  Fly   421 GRVNCNSYLVTDRVAFIGTSSFSGEHFTYSAGIGLVLQDMEYNNNSLRTDLMAIFLRDWFSPYA 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLD3	NP_036400.2	PHA02820	77..490	CDD:222934	179/412 (43%)
CG43345	NP_610096.1	PHA02820	98..487	CDD:222934	177/402 (44%)