Sequence 1: | NP_036236.1 | Gene: | BACE1 / 23621 | HGNCID: | 933 | Length: | 501 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_650622.1 | Gene: | CG5860 / 42095 | FlyBaseID: | FBgn0038506 | Length: | 370 | Species: | Drosophila melanogaster |
Alignment Length: | 457 | Identity: | 99/457 - (21%) |
---|---|---|---|
Similarity: | 172/457 - (37%) | Gaps: | 131/457 - (28%) |
- Green bases have known domain annotations that are detailed below.
Human 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPL--------------RSGL-GGAPLGLRLPRETDEE 50
Human 51 PEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------ 109
Human 110 HRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFI--- 171
Human 172 --NGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGS 234
Human 235 MIIGGIDHSLYTGSLWYTPIRR--EWYYEVIIVRV---EINGQDLKMDCKEYNYDKSIVDSGTTN 294
Human 295 LRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNI--------FPVISL-YLMG 350
Human 351 EVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTG-TVMGAVIMEGFYVVFDRARKRIG 414
Human 415 FA 416 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
BACE1 | NP_036236.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 39..58 | 5/18 (28%) | |
beta_secretase_like | 72..437 | CDD:133140 | 82/371 (22%) | ||
Interaction with RTN3 | 479..501 | ||||
DXXLL. /evidence=ECO:0000269|PubMed:15886016 | 496..500 | ||||
CG5860 | NP_650622.1 | pepsin_retropepsin_like | 61..368 | CDD:299705 | 83/393 (21%) |
Asp | 63..369 | CDD:278455 | 83/391 (21%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1339 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |