DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZMYND8 and png2

DIOPT Version :9

Sequence 1:	NP_001350643.1	Gene:	ZMYND8 / 23613	HGNCID:	9397	Length:	1241	Species:	Homo sapiens
Sequence 2:	NP_001342766.1	Gene:	png2 / 2539953	PomBaseID:	SPBC1709.11c	Length:	305	Species:	Schizosaccharomyces pombe

Alignment Length:	133	Identity:	42/133 - (31%)
Similarity:	61/133 - (45%)	Gaps:	28/133 - (21%)

- Green bases have known domain annotations that are detailed below.

Human    37 PGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPL- 100
            |....:.|..||..|||.||..|:||.|...|:::.:  ..|...|.|              ||
pombe   184 PTKRRKNAVPRKSSSPPLSSTKHAPQSTERRPVRRSE--SRLKQTNGE--------------PLV 232

Human   101 ---TTDPVDVVPQDGRNDFYCWVCHR--EGQVLCC--ELCPRV-YHAKCLRLTSEPEGDWFCPEC 157
               |.|..| :.::| ...||: |.:  .||::.|  |.|.|. :|..|:.|...|:|.|:|.||
pombe   233 KHDTLDSSD-ISREG-EQLYCY-CQQVSYGQMIGCDNENCKREWFHLPCVGLVEPPKGIWYCKEC 294

Human   158 EKI 160
            |::
pombe   295 EEL 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZMYND8	NP_001350643.1	ING	<31..160	CDD:331088	42/131 (32%)
		PHD_PRKCBP1	117..157	CDD:277013	16/44 (36%)
		Bromo_RACK7	178..276	CDD:99940
		BS69_related	296..376	CDD:99902
		DUF3544	445..647	CDD:314873
		MIP-T3	<634..>795	CDD:313469
		DUF1640	960..>1051	CDD:311647
		zf-MYND	1055..1089	CDD:307734
png2	NP_001342766.1	TNG2	6..298	CDD:227367	42/133 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910