DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZMYND8 and bra-2

DIOPT Version :10

Sequence 1:NP_001350643.1 Gene:ZMYND8 / 23613 HGNCID:9397 Length:1241 Species:Homo sapiens
Sequence 2:NP_497292.1 Gene:bra-2 / 175255 WormBaseID:WBGene00017757 Length:214 Species:Caenorhabditis elegans


Alignment Length:205 Identity:60/205 - (29%)
Similarity:95/205 - (46%) Gaps:30/205 - (14%)


- Green bases have known domain annotations that are detailed below.


Human   913 LVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSK 977
            ::...|...:|...|.:.  :|.::.||    ..|.:..::.:|....:...:| |..:..||.:
 Worm    11 MMDQQQQQGVVPQQGDIH--LSPIDKDL----GDAALENNVRQYHLDGVVVSEG-MKRMIIDLQR 68

Human   978 NTTGSTIAEIRRLRIEI-EKL--------QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 1033
            :......|...:..:|: |||        |.:..:.|.:.|..||.|.|::.   .:.|:.|..|
 Worm    69 HWLSEYHASREKCLVELTEKLHQEFMMDQQKIRSELLQQFKDELEQTRADLE---NKHRENLKME 130

Human  1034 VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ------- 1091
            ..|..|..|::.| .::|||||.:|..|||::|||||:||...|||.||..|.|.|.:       
 Worm   131 SAKLNEKHKRELV-ASRKKQWCWSCDNEAIYHCCWNTAYCSVECQQGHWQTHRKFCRRKKGNNAP 194

Human  1092 ---SATAPQQ 1098
               |..||||
 Worm   195 GAPSVPAPQQ 204

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZMYND8NP_001350643.1 TNG2 <31..160 CDD:227367
PHD_PRKCBP1 117..157 CDD:277013
Bromo_RACK7 178..276 CDD:99940
PWWP_PRKCBP1 299..389 CDD:438988
DUF3544 449..647 CDD:463452
TFIIF_alpha <629..>787 CDD:310411
AtpF <984..>1051 CDD:440475 19/75 (25%)
zf-MYND 1055..1089 CDD:460312 19/33 (58%)
bra-2NP_497292.1 zf-MYND 151..185 CDD:460312 19/33 (58%)
Blue background indicates that the domain is not in the aligned region.

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