DRSC/TRiP Functional Genomics Resources

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Protein Alignment DAPK2 and CG10177

DIOPT Version :10

Sequence 1:NP_001350659.1 Gene:DAPK2 / 23604 HGNCID:2675 Length:488 Species:Homo sapiens
Sequence 2:NP_651150.1 Gene:CG10177 / 42772 FlyBaseID:FBgn0039083 Length:411 Species:Drosophila melanogaster


Alignment Length:281 Identity:69/281 - (24%)
Similarity:131/281 - (46%) Gaps:20/281 - (7%)


- Green bases have known domain annotations that are detailed below.


Human     5 SMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSRE 69
            ||:|.::....|..:|..    |.:......::.:.:.::...:...|.:.| |::::.||    
  Fly   135 SMKSHDLPEAIQLYIETI----EPVEHNTRTLIYRGQTRANRTKCTVKMVNK-QTQSNDRG---- 190

Human    70 EIEREVSILRQVLHH-NVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQI 133
            :...|..:|||:..| |:|.|....|:...:..:||.:. ..:...:.::..|||.:|.|.::..
  Fly   191 DTYMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLD-CNMQKVIQKRGILSEADARSVMRCT 254

Human   134 LDGVNYLHTKKIAHFDLKPENIMLLDK----NIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194
            :..:.::|..::.|.|:||||:::...    |..:  :|:.:|.||.... |.:.....|||.::
  Fly   255 VSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKM--VKVANFDLATYYR-GSKLYVRCGTPCYM 316

Human   195 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTK--QETLANITAVSYDFDEEFFSQTSEL 257
            |||::.......:.|.||:||..:.:|.|..||....|  :|..|.|.:....:.::..|..|..
  Fly   317 APEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPE 381

Human   258 AKDFIRKLLVKETRKRLTIQE 278
            |...|..|||.:...|:.|.|
  Fly   382 ATQLIDGLLVSDPSYRVPIAE 402

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DAPK2NP_001350659.1 STKc_DAPK2 17..285 CDD:271098 65/269 (24%)
CG10177NP_651150.1 DCX 18..108 CDD:214711
S_TKc 164..409 CDD:214567 63/248 (25%)
Blue background indicates that the domain is not in the aligned region.

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