Protein Alignment DAPK2 and Mekk1

DIOPT Version :9

• Sequence 1: NP_001350659.1
• Gene: DAPK2 / 23604
• HGNCID: 2675
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Alignment Length: 301
• Identity: 81/301 - (26%)
• Similarity: 130/301 - (43%)
• Gaps: 48/301 - (15%)

Human     5 SMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSR- 68
            |:.|.:....:.:.|...:..|.::|.|:|..|......:||...|.|.|      |.:.|.:|
  Fly  1264 SLNSSDKVHIRARSVHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEI------AIQPGETRA 1322

Human    69 -EEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQ 132
             :.:..|:.||..:.|.|::..:.:..:|.::::.:||.|.|.|...:....:|.|.....|..|
  Fly  1323 LKNVAEELKILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQ 1387

Human   133 ILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGV----EFKNIFGTPEF 193
            :|.||:.||...|.|.|:|..||.|:|.:   ..:||.|||.|.:|:...    |.:...||..:
  Fly  1388 LLSGVSELHKHGIVHRDIKTANIFLVDGS---NSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAY 1449

Human   194 VAPEI---VNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFF---- 251
            :|||:   .|.:..|..||:||:|.:...:.||..|:.                .||..|.
  Fly  1450 MAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWA----------------QFDSNFQIMFK 1498

Human   252 ----------SQTSELAKDFIRKLLVKETRKRLTIQEALRH 282
                      ...|:...|||...|..:.::|||..|.|.|
  Fly  1499 VGMGEKPQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEH 1539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAPK2	NP_001350659.1	STKc_DAPK2	17..285	CDD:271098	79/289 (27%)
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	78/284 (27%)
		S_TKc	1282..1541	CDD:214567	78/283 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910