Protein Alignment AMACR and Amacr

DIOPT Version :10

• Sequence 1: NP_001161067.1
• Gene: AMACR / 23600
• HGNCID: 451
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_610054.1
• Gene: Amacr / 35337
• FlyBaseID: FBgn0032881
• Length: 373
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 186/336 - (55%)
• Similarity: 237/336 - (70%)
• Gaps: 6/336 - (1%)

Human     1 MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDR-PGSRYDVSRLGRGKRSLVLDLKQPRGAA 64
            |.|:||.|:|..||||||||..:|.||||.|.|:|: ..:..||  |.:|||:|.||||.|:|..
  Fly     1 MPLKGIRVLEFVGLAPGPFCGKILTDFGATVTRIDKVMENPLDV--LQQGKRTLCLDLKNPKGQQ 63

Human    65 VLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLAL 129
            .::||.|:.|||:||||.||||||.|||..|...|||||||||:||||.|...:.|||||||.||
  Fly    64 AVQRLVKKCDVLIEPFRPGVMEKLNLGPTDLCTANPRLIYARLTGFGQHGRLAQRAGHDINYAAL 128

Human   130 SGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMVEGTAYLSSF 194
            |||||.:||..|...||:|:|||||||.|||||||.:||.:|.|:|||||:||:||||.||::|:
  Fly   129 SGVLSMLGRRHEKVTAPINILADFAGGSLMCALGICLALLERHRSGKGQVVDASMVEGAAYVASW 193

Human   195 LWKTQKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIKGLGLKSDELPNQM 259
            |:.::.|.:|...||.|::|||:.||.||.|.||.:|:|||:||||:|:|.:.|.|..|  .:|.
  Fly   194 LFMSRNLVIWGRERGDNLVDGGSFFYDTYETKDGRYMSVGALEPQFFEMLKQRLELPED--VSQF 256

Human   260 SMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVS 324
            ..:.....:|...:.|..||:|||.|||:..||||.|||.:.||..||||.:|.||..:|: ..:
  Fly   257 GEEHQVRGRKLLTEAFLSKTQAEWSQIFEDVDACVYPVLDYREVHRHDHNIQRNSFEVTED-TAT 320

Human   325 PRPAPLLLNTP 335
            |||||:|..||
  Fly   321 PRPAPVLSRTP 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMACR	NP_001161067.1	CaiB	1..373	CDD:441409	186/336 (55%)
Amacr	NP_610054.1	CaiB	1..366	CDD:441409	186/336 (55%)