DRSC/TRiP Functional Genomics Resources

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Protein Alignment PATZ1 and CG10321

DIOPT Version :9

Sequence 1:NP_055138.2 Gene:PATZ1 / 23598 HGNCID:13071 Length:687 Species:Homo sapiens
Sequence 2:NP_001261124.1 Gene:CG10321 / 37464 FlyBaseID:FBgn0034643 Length:855 Species:Drosophila melanogaster


Alignment Length:331 Identity:77/331 - (23%)
Similarity:110/331 - (33%) Gaps:99/331 - (29%)


- Green bases have known domain annotations that are detailed below.


Human   245 QLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQ 309
            :.|..|..:|:|::|  |.||.    :::|                                   
  Fly   528 EALVGPTMTVSSASP--TPKRA----KRSN----------------------------------- 551

Human   310 HEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLN--- 371
            |:...|||   |...|..||..|.     :.........||...|.|..|......|.|.::   
  Fly   552 HQIPAGVT---LEPCDHQPPAAGS-----TTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANL 608

Human   372 -----RHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHD----GSVGKPYICQSCGKGFSRPDH 427
                 |...|..|...|.|.:|...|::...:..|:.||.    .:..|...||.|.|.|..|..
  Fly   609 VTEFIRQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGM 673

Human   428 LNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEG 492
            |..|:|..........|..||.:|.::..|..|...|:.:..|  ||                  
  Fly   674 LRMHMKTHDAESSTPMCTICNRTFKSKAILYRHRQTHQQRAYC--CG------------------ 718

Human   493 PSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNKEGQKCSHQD 557
                .:.|.:.||||..||.||:..|    |:|   .:|:...|   .|...|.|.:    |.|.
  Fly   719 ----VANCRKNFSSAVNLKWHVERKH----PEV---VDPLFKCG---ECGSLYDNVD----SLQL 765

Human   558 PIESSD 563
            .:||:|
  Fly   766 HVESTD 771

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PATZ1NP_055138.2 BTB_POZ_ZBTB19_PATZ1 14..162 CDD:349516
A-T hook domain 264..272 2/7 (29%)
Zn finger DNA binding domain 294..628 68/282 (24%)
C2H2 Zn finger 294..314 CDD:275368 1/19 (5%)
C2H2 Zn finger 357..377 CDD:275368 4/27 (15%)
zf-C2H2 357..377 CDD:395048 4/27 (15%)
COG5048 <381..518 CDD:227381 36/140 (26%)
C2H2 Zn finger 385..405 CDD:275368 4/19 (21%)
C2H2 Zn finger 415..433 CDD:275368 8/17 (47%)
C2H2 Zn finger 444..464 CDD:275368 6/19 (32%)
C2H2 Zn finger 497..517 CDD:275368 9/19 (47%)
zf-C2H2_assoc3 536..604 CDD:406930 9/28 (32%)
C2H2 Zn finger 607..628 CDD:275370
CG10321NP_001261124.1 zf-AD 12..80 CDD:214871
ASF1_hist_chap <405..516 CDD:304562
C2H2 Zn finger 627..647 CDD:275368 4/19 (21%)
C2H2 Zn finger 661..681 CDD:275368 9/19 (47%)
C2H2 Zn finger 690..710 CDD:275368 6/19 (32%)
C2H2 Zn finger 717..740 CDD:275368 11/44 (25%)
C2H2 Zn finger 750..767 CDD:275368 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24399
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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