DRSC/TRiP Functional Genomics Resources

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Protein Alignment VSIG2 and DIP-delta

DIOPT Version :9

Sequence 1:NP_055127.2 Gene:VSIG2 / 23584 HGNCID:17149 Length:327 Species:Homo sapiens
Sequence 2:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster


Alignment Length:268 Identity:63/268 - (23%)
Similarity:99/268 - (36%) Gaps:49/268 - (18%)


- Green bases have known domain annotations that are detailed below.


Human     5 PGPFLCGALLGFLCLSGLAVEVKV-------PTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFV 62
            |..|....::..:.::.|...|.:       |...::..:|:.|.|.|......|  :.:.|   
  Fly    18 PSRFTNRRIMFLIYMTNLVTHVMMDEPRFAQPIPNVTVAVGRDANLPCVVEHLGG--YKVAW--- 77

Human    63 QPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPP 127
                 |.....::...:.|:.   |:..|.|:..   |.....|.:...|..|.|.|:||||..|
  Fly    78 -----IHIDRQMILTIHRHVI---SRIPRYSITY---TDNTWLLHVNQAHQDDRGYYMCQVNTNP 131

Human   128 DFYTNGLGLINLTVLVPPSNPLCSQSGQTSV----GGSTALRCSSSEGAPKPVYNWVRLGTFPTP 188
            .....|.    |.|:||| |.|..:|..:||    ..:..:.| .::|.|.|...|.|       
  Fly   132 MISQVGY----LQVVVPP-NILDIESTPSSVAVRENQNINMTC-RADGFPAPKIIWRR------- 183

Human   189 SPGSMVQDEVSGQLI--------LTNLSLTSSGTYRCVATNQM-GSASCELTLSVTEPSQGRVAG 244
            ..|..:..|...:::        ||.:|....|.|.|:|||.: .|.|..:.|.|.......|..
  Fly   184 EDGEEIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSVSKRIILDVEFSPMIWVPN 248

Human   245 ALIGVLLG 252
            .|:|...|
  Fly   249 QLVGAPSG 256

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VSIG2NP_055127.2 V-set 31..142 CDD:311561 24/110 (22%)
Ig 164..231 CDD:319273 19/75 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 305..327
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 25/111 (23%)
Ig 145..238 CDD:416386 26/101 (26%)
Ig strand A 145..149 CDD:409353 2/4 (50%)
Ig strand A' 154..159 CDD:409353 2/4 (50%)
Ig strand B 165..172 CDD:409353 1/7 (14%)
Ig strand C 178..183 CDD:409353 1/4 (25%)
Ig strand C' 185..187 CDD:409353 0/1 (0%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 1/5 (20%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 4/15 (27%)
Ig strand A' 250..253 CDD:409353 1/2 (50%)
Ig strand B 259..266 CDD:409353
Ig strand C 272..277 CDD:409353
Ig strand C' 281..283 CDD:409353
Ig strand D 289..293 CDD:409353
Ig strand E 295..305 CDD:409353
Ig strand F 314..322 CDD:409353
Ig strand G 325..334 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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