DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment VSIG2 and dpr5

DIOPT Version :9

Sequence 1:	NP_055127.2	Gene:	VSIG2 / 23584	HGNCID:	17149	Length:	327	Species:	Homo sapiens
Sequence 2:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	56/256 - (21%)
Similarity:	85/256 - (33%)	Gaps:	75/256 - (29%)

- Green bases have known domain annotations that are detailed below.

Human    37 LGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTV 101
            ||.||.|.|.. ..:||. |:.|                           .:.:.:.:|    |:
  Fly   104 LGTTARLHCRV-RHLGDR-AVSW---------------------------IRQRDLHIL----TI 135

Human   102 GVAT-------------------LKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSN 147
            |:.|                   ||:..|...|.|.|.|||:..|....    ...|.|:...:.
  Fly   136 GIMTYTNDQRFLARHIDNSDEWVLKIVSVQQRDAGVYECQVSTEPKISL----AYKLVVVTSKAQ 196

Human   148 PLCSQSGQTSVGGSTALRCSSSEGAPKPVYN--WVRLGTFPTPSP--GSMVQDE---VSGQLILT 205
            .|.::......|....|.|.:.: ||.|..:  |.:.....:.|.  |..|:.|   .:..|:::
  Fly   197 ILANRELFIQSGSDINLTCIAPQ-APGPYTHMLWHKDTELVSDSARGGIRVESEQQMKTSNLVIS 260

Human   206 NLSLTSSGTYRCVATN-QMGSASCELTLSVTEPSQGRVAGA----------LIGVLLGVLL 255
            .:..|.||.|.|.|.| ...|....:..|....:.....|:          |:.|||.|||
  Fly   261 RVQHTDSGNYTCSADNSNSDSVFVHIIKSEQHAAMQHELGSRLLLPPLPLLLLAVLLVVLL 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VSIG2	NP_055127.2	V-set	31..142	CDD:311561	25/123 (20%)
		Ig	164..231	CDD:319273	19/74 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..327
dpr5	NP_650080.3	V-set	95..191	CDD:284989	25/123 (20%)
		IG_like	98..179	CDD:214653	23/107 (21%)
		IG_like	206..278	CDD:214653	19/72 (26%)
		Ig	211..278	CDD:143165	18/67 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910