DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VSIG2 and dpr16

DIOPT Version :9

Sequence 1:	NP_055127.2	Gene:	VSIG2 / 23584	HGNCID:	17149	Length:	327	Species:	Homo sapiens
Sequence 2:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	46/212 - (21%)
Similarity:	70/212 - (33%)	Gaps:	63/212 - (29%)

- Green bases have known domain annotations that are detailed below.

Human    38 GKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVG 102
            |.....|.|...::|:|||                        |..|.|.:....|.|.
  Fly   269 GGALSTTATPVAALGNSFA------------------------HAVPGGQERGNSSSLS------ 303

Human   103 VATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRC- 166
             .||::..|:..|.|.|.||:...|.....    :.|.|:.|.:..:..:......|....|.|
  Fly   304 -WTLQIKYVNLEDAGWYECQLATEPKMSAK----VQLFVITPRTELIGDRQRFVKAGSRVELHCI 363

Human   167 -SSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCEL 230
             ..:..|||.:: |.|.....|      .::|.||         ..||.|..:..|..||
  Fly   364 VRGTLEAPKYIF-WYRGDQQVT------AENEASG---------AQSGWYTQIDRNIFGS----- 407

Human   231 TLSVTEPSQGRVAGALI 247
                ||.::..: |:|:
  Fly   408 ----TEHNRNTI-GSLV 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VSIG2	NP_055127.2	V-set	31..142	CDD:311561	22/103 (21%)
		Ig	164..231	CDD:319273	17/68 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..327
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	22/102 (22%)
		Ig	<298..338	CDD:299845	12/50 (24%)
		IG_like	352..447	CDD:214653	22/94 (23%)
		Ig	358..439	CDD:143165	21/88 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910