Protein Alignment VSIG2 and dpr1

DIOPT Version :10

• Sequence 1: NP_055127.2
• Gene: VSIG2 / 23584
• HGNCID: 17149
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_995908.2
• Gene: dpr1 / 2768858
• FlyBaseID: FBgn0040726
• Length: 367
• Species: Drosophila melanogaster
• Alignment Length: 392
• Identity: 76/392 - (19%)
• Similarity: 122/392 - (31%)
• Gaps: 136/392 - (34%)

Human    13 LLGFLCLSGLAV-----EVKVPTEP-----------------------LSTPLGKTAELTCTYST 49
            |:|:|.|..:.:     ....||.|                       |:..:|:|..|.|...
  Fly    15 LIGWLLLLSMVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVE- 78

Human    50 SVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPS 114
            .:||. .:.|        |.:....:....|..|   :..:|..:|: |......||::....|.
  Fly    79 RLGDK-DVSW--------IRKRDLHILTAGGTTY---TSDQRFQVLR-PDGSANWTLQIKYPQPR 130

Human   115 DTGTYLCQVNNPPDF---YTNGLGLINLTV-LVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKP 175
            |:|.|.||:|..|..   ||  ..::.|.. :..||:.:      ...|....|.|...:| |..
  Fly   131 DSGVYECQINTEPKMSLSYT--FNVVELKAEIFGPSDLM------VKTGSDINLTCKIMQG-PHE 186

Human   176 VYN--WVRLGTFPTPSPG------SMVQ--------DEVSGQLILTNLSLTSSGTYRCVATNQMG 224
            :.|  |.: |:......|      ||.:        |.::.:|.:.......:|.|.||
  Fly   187 LGNIFWYK-GSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCV------ 244

Human   225 SASCELTLSVTEPSQGRVAGALIGVLLG----------------------VLLLSVAAFCLVRF- 266
                        |:..:.:...:.|::|                      .:|||:.:.||..|
  Fly   245 ------------PTVAKTSSVYVHVIIGEHPAAMQHNSSSNSNSFYCGICCMLLSIVSCCLQHFY 297

Human   267 -------------QKERGKKP--------KETYGGSDLREDAIAPGISEHTCMRADSSKGFLERP 310
                         .|..|..|        .||  |....|.|.|.|.|........:.....|||
  Fly   298 ETGCGYLHAAAALAKSAGLGPPKRATLTTSET--GISAAEVAAAAGASAAVASALATCNMLRERP 360

Human   311 SS 312
            ::
  Fly   361 AA 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VSIG2	NP_055127.2	V-set	31..142	CDD:462230	28/137 (20%)
		Ig	152..232	CDD:472250	17/95 (18%)
		Ig strand B	162..166	CDD:409353	1/3 (33%)
		Ig strand C	176..180	CDD:409353	1/5 (20%)
		Ig strand E	200..204	CDD:409353	1/3 (33%)
		Ig strand F	214..219	CDD:409353	2/4 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..327		3/8 (38%)
dpr1	NP_995908.2	Ig	53..138	CDD:472250	20/98 (20%)
		Ig strand A'	63..65	CDD:409355	1/1 (100%)
		Ig strand B	69..77	CDD:409355	3/7 (43%)
		CDR1	77..83	CDD:409355	1/6 (17%)
		Ig strand C	84..90	CDD:409355	2/13 (15%)
		CDR2	93..109	CDD:409355	2/18 (11%)
		Ig strand D	109..114	CDD:409355	1/5 (20%)
		FR3	110..147	CDD:409355	12/37 (32%)
		Ig strand E	119..125	CDD:409355	2/5 (40%)
		Ig strand F	133..148	CDD:409355	6/14 (43%)
		CDR3	148..160	CDD:409355	3/13 (23%)
		IG_like	163..257	CDD:214653	20/119 (17%)
		Ig strand B	174..178	CDD:409355	1/3 (33%)
		Ig strand C	189..193	CDD:409355	1/3 (33%)
		Ig strand E	226..230	CDD:409355	1/3 (33%)
		Ig strand F	240..244	CDD:409355	1/3 (33%)