Protein Alignment ZNF346 and CG1231

DIOPT Version :10

• Sequence 1: NP_001295142.1
• Gene: ZNF346 / 23567
• HGNCID: 16403
• Length: 319
• Species: Homo sapiens
• Sequence 2: NP_612032.1
• Gene: CG1231 / 38060
• FlyBaseID: FBgn0035134
• Length: 345
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 64/254 - (25%)
• Similarity: 99/254 - (38%)
• Gaps: 69/254 - (27%)

Human   100 CKVCCALLISESQKLAHYQSKKHANKVKRYLAIH----GMETLKGETKKLDSDQKSSRSKDKNQC 160
            |::|...:.|..:...||:||.|...:..:||.:    |:|.  ...|:|   .|...:......
  Fly   104 CQLCKVQMTSRKRARDHYESKAHDRHISAWLAKNYTEVGLEA--PPVKRL---AKQGPTGPNAFH 163

Human   161 CPICNMTFSSPVVAQSHYLGKTHAK------------------------NLKLKQQS-TK---VE 197
            |.:||:..:|.:.|:.||||:.|.:                        :|..|.:| ||   .:
  Fly   164 CELCNLDLTSSMHARQHYLGRKHKRVEQGVAKPSGARHCDTSVGRYGIGSLFRKPESLTKDSPTD 228

Human   198 ALHQNREMI---DPDKFCSLCHATFNDPVMAQQHYVGKKHRKQ----------------ETKLKL 243
            .|.....:|   |.::.|.||..........|.|..|.:|:|.                ||: ||
  Fly   229 VLISENSVIKSDDNERTCHLCKIVVTSAAQMQAHLAGARHQKNWRTSRQDQNHSEAPIPETE-KL 292

Human   244 MARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKH----KN--QSPKTV 296
            .|     |:.|:...|.|: |.|:.|.:::|.....|.|..|.||    ||  |:.|.|
  Fly   293 DA-----AELALYRTPMGQ-YYCQPCNMMMNHESTLQQHFIGKKHLKRVKNLSQTEKNV 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF346	NP_001295142.1	ZnF_U1	96..129	CDD:197732	8/28 (29%)
		ZnF_U1	160..189	CDD:197732	11/52 (21%)
		C2H2 Zn finger	161..183	CDD:275371	9/21 (43%)
		ZnF_U1	207..241	CDD:197732	11/49 (22%)
		C2H2 Zn finger	212..234	CDD:275371	6/21 (29%)
		C2H2 Zn finger	266..288	CDD:275371	6/21 (29%)
CG1231	NP_612032.1	C2H2 Zn finger	104..163	CDD:275371	15/63 (24%)
		zf-met	104..126	CDD:463736	7/21 (33%)
		zf-met	162..186	CDD:463736	9/23 (39%)
		C2H2 Zn finger	164..186	CDD:275371	9/21 (43%)
		zf-met	245..268	CDD:463736	6/22 (27%)
		ZnF_U1	304..336	CDD:197732	10/32 (31%)