Protein Alignment TSPAN15 and Tsp39D

DIOPT Version :10

• Sequence 1: NP_036471.1
• Gene: TSPAN15 / 23555
• HGNCID: 23298
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_523612.3
• Gene: Tsp39D / 35405
• FlyBaseID: FBgn0032943
• Length: 235
• Species: Drosophila melanogaster
• Alignment Length: 246
• Identity: 53/246 - (21%)
• Similarity: 105/246 - (42%)
• Gaps: 50/246 - (20%)

Human    20 LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLES--AFLAPAIILILLGVVMFMVSFIGVL 82
            :|:.....:.:|.|.|.|:..||...::....|....|  .:.|| |||:::|..:.::.|:|..
  Fly     9 VKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYSNFVSDHVWTAP-IILMIVGAAVAVICFLGCC 72

Human    83 ASLRDNLYLLQAFMYILGICLIMEL---IGGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFKNI 144
            .:|:::..::.:|..:..:..:.|:   :.|.|..|..:|   .:.......:::|.:..|:::.
  Fly    73 GALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQ---IMESQFNSTMQHYKERADYRDA 134

Human   145 MDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFS 209
            ...:|.:..|||.....|| :..|.:.:.|.  ||     |.:.|.:|.           ||
  Fly   135 WTLLQTELDCCGINGPNDW-ETVYRNSTLPA--AC-----CSVINLSEA-----------KE--- 177

Human   210 VQDVIYVRGCTNA---------VIIWFMDNYT-IMAGILLGILLPQFLGVL 250
                     |||.         .::..:|:.| |:|.::||:...|.|.:|
  Fly   178 ---------CTNTHATQHGCLQKLLEILDSKTLILASVVLGVAGIQMLTIL 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN15	NP_036471.1	Tetraspanin	20..>157	CDD:459767	29/141 (21%)
		penumbra_like_LEL	114..231	CDD:239411	23/125 (18%)
Tsp39D	NP_523612.3	Tetraspanin	9..226	CDD:459767	53/246 (22%)
		tetraspanin_LEL	131..>167	CDD:351888	10/43 (23%)