Protein Alignment TSPAN12 and Tsp5D

DIOPT Version :10

• Sequence 1: NP_036470.1
• Gene: TSPAN12 / 23554
• HGNCID: 21641
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 65/285 - (22%)
• Similarity: 107/285 - (37%)
• Gaps: 73/285 - (25%)

Human     9 CLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCF 73
            |:|.....||::.||.|.:.|....|:|.......||..:               |..:.|...|
  Fly     8 CIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQ---------------HAGLSADTIF 57

Human    74 L------IIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV----------WTYEQELMVP 122
            :      .:|...|.||...::..||..||..::::|..|...|.          .|...||...
  Fly    58 MGIGGTGFVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFG 122

Human   123 VQ----WSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWP-----P 178
            ::    .||..:|.|..          :...|:..|:.|:||||..:.||.::  ..||     |
  Fly   123 IERHYNSSDRGSLVAPS----------VASIWDSVQQSFECCGVSSYEDWYDI--QSWPGRRWVP 175

Human   179 DSCCVREF----------------PGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLG 227
            :|||...:                |.|.:   .|:.|..:.:||...:.|:..|  ||.|:..:|
  Fly   176 ESCCRTLYDQRQVLTEGSGDGMMRPDCGR---SENPSLWWDKGCAHSLQSWFTG--QLNVVGAVG 235

Human   228 ISIGVTQILAMILTITLLWALYYDR 252
            :.|...|:..:|.::.|...:.:.|
  Fly   236 LGIAFVQLFGLITSMLLFCTVKHKR 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN12	NP_036470.1	Tetraspanin	10..246	CDD:459767	63/276 (23%)
		TM4SF12_like_LEL	116..218	CDD:239410	29/126 (23%)
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	63/276 (23%)
		NET-5_like_LEL	105..228	CDD:239418	30/139 (22%)