Protein Alignment CDK20 and KIN28

DIOPT Version :9

• Sequence 1: XP_016870050.1
• Gene: CDK20 / 23552
• HGNCID: 21420
• Length: 351
• Species: Homo sapiens
• Sequence 2: NP_010175.1
• Gene: KIN28 / 851450
• SGDID: S000002266
• Length: 306
• Species: Saccharomyces cerevisiae
• Alignment Length: 304
• Identity: 117/304 - (38%)
• Similarity: 169/304 - (55%)
• Gaps: 16/304 - (5%)

Human     9 RIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPH 73
            ::|||.:.:|:......||..:|:|::.....:||....|:||:|.||||: :..|::|..:|..
Yeast    12 KVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQ-HPNVIELIDIFMA 75

Human    74 GGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISAS 138
            .....|..||:.:||..|::........|.:|:::.|.|:||..||.|.|:||||||.|||.|..
Yeast    76 YDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPD 140

Human   139 GQLKIADFGLARVF-SPDGSRLYTHQVATSPLPRRWYRAPELLYGARQYDQGVDLWSVGCIMGEL 202
            ||:|:|||||||.. :|       |::.||.:..|||||||||:||:.|...:|:||||.|..||
Yeast   141 GQIKVADFGLARAIPAP-------HEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAEL 198

Human   203 LNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPD----VS 263
            :...|..||:||::|:....|.||||..:.|||::....|||:..   .|.|..:.|..    .|
Yeast   199 MLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQI---YPPPSRDELRKRFIAAS 260

Human   264 PQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPI 307
            ..|||.:...|...|.:|..|.:.|...||...|.|:.||.:.|
Yeast   261 EYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSDPSSIKI 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK20	XP_016870050.1	None
KIN28	NP_010175.1	STKc_CDK7	7..302	CDD:270833	116/300 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810