DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CDK20 and mcs6

DIOPT Version :9

Sequence 1:XP_016870050.1 Gene:CDK20 / 23552 HGNCID:21420 Length:351 Species:Homo sapiens
Sequence 2:NP_596349.1 Gene:mcs6 / 2540471 PomBaseID:SPBC19F8.07 Length:335 Species:Schizosaccharomyces pombe


Alignment Length:309 Identity:129/309 - (41%)
Similarity:181/309 - (58%) Gaps:19/309 - (6%)


- Green bases have known domain annotations that are detailed below.


Human     9 RIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQE-MEDNQYVVQLKAVFP 72
            ::|||.:.:||..:..||...||:||:.:.:.:||....||||||.|:| ..||  |::|..||.
pombe    16 KVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDN--VIELVDVFS 78

Human    73 HGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISA 137
            ......:..||:.|||..:::........|.:||::.|||:|:...|:..|:||||||.|||||:
pombe    79 TKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISS 143

Human   138 SGQLKIADFGLARVFSPDGSRLYTHQVATSPLPRRWYRAPELLYGARQYDQGVDLWSVGCIMGEL 202
            .|.||:|||||:|.|.....  .:|||.|     ||||.|||..|.|.|..|||:||||||..||
pombe   144 DGVLKLADFGLSRDFGTPSH--MSHQVIT-----RWYRPPELFMGCRSYGTGVDMWSVGCIFAEL 201

Human   203 LNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMP---LEEVLPDVSP 264
            :..:|..||::|::||..:.|.||||.|:|...:.:||:|.::   :.:|.|   :|.:......
pombe   202 MLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVEM---KHIPPPNGGMEALFSAAGH 263

Human   265 QALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGG 313
            :.:|||...|.|.|::|..|.:||.|.||...|.|.|||.||   |.||
pombe   264 EEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPKPTHPSLLP---RKGG 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CDK20XP_016870050.1 None
mcs6NP_596349.1 STKc_CDK7 11..305 CDD:270833 124/300 (41%)
Pkinase 11..292 CDD:278497 117/287 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0659
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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